Aspergillus endophthalmitis resulting in development of retinal aspergilloma

Lee Kiang; Ashkan Pirouz; Scott Grant; Sean D. Adrean; Mehrdad Malihi; Phoebe Lin

doi:10.3928/23258160-20170802-13

Aspergillus endophthalmitis resulting in development of retinal aspergilloma

Lee Kiang, Ashkan Pirouz, Scott Grant, Sean D. Adrean, Mehrdad Malihi, Phoebe Lin

Ophthalmology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A 78-year-old immunocompetent man presented with a 3-month history of painless decreased vision and panuveitis with a macular lesion presumed to be due to endogenous endophthalmitis. He had been treated with systemic, intravenous, and intravitreal antibiotics and antifungal agents as well as intravitreal steroids. A culture from a prior vitrectomy had grown a single colony of Aspergillus thought to be a contaminant. The macular lesion enlarged and caused a tractional retinal detachment. The patient underwent surgery including resection of what appeared to be an invasive retinal aspergilloma, from which polymerase chain reaction and histopathology confirmed Aspergillus fumigatus.

Original language	English (US)
Pages (from-to)	680-683
Number of pages	4
Journal	Ophthalmic Surgery Lasers and Imaging Retina
Volume	48
Issue number	8
DOIs	https://doi.org/10.3928/23258160-20170802-13
State	Published - Aug 2017

ASJC Scopus subject areas

Surgery
Ophthalmology

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title = "Aspergillus endophthalmitis resulting in development of retinal aspergilloma",

abstract = "A 78-year-old immunocompetent man presented with a 3-month history of painless decreased vision and panuveitis with a macular lesion presumed to be due to endogenous endophthalmitis. He had been treated with systemic, intravenous, and intravitreal antibiotics and antifungal agents as well as intravitreal steroids. A culture from a prior vitrectomy had grown a single colony of Aspergillus thought to be a contaminant. The macular lesion enlarged and caused a tractional retinal detachment. The patient underwent surgery including resection of what appeared to be an invasive retinal aspergilloma, from which polymerase chain reaction and histopathology confirmed Aspergillus fumigatus.",

author = "Lee Kiang and Ashkan Pirouz and Scott Grant and Adrean, {Sean D.} and Mehrdad Malihi and Phoebe Lin",

note = "Funding Information: Originally submitted December 20, 2016. Revision received March 28, 2017. Accepted for publication June 2, 2017. This research is partially supported by a Research to Prevent Blindness departmental grant and by core grant P30 EY010572 from the NIH. Lee Kiang, MD, PhD, is a fellow of the Heed Ophthalmic Foundation. The authors report no relevant financial disclosures. Address correspondence to Phoebe Lin, MD, PhD, Assistant Professor of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, 3375 SW Terwilliger Blvd., Portland, OR 97239; email: linp@ohsu.edu. doi: 10.3928/23258160-20170802-13",

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AU - Grant, Scott

AU - Adrean, Sean D.

AU - Malihi, Mehrdad

AU - Lin, Phoebe

N1 - Funding Information: Originally submitted December 20, 2016. Revision received March 28, 2017. Accepted for publication June 2, 2017. This research is partially supported by a Research to Prevent Blindness departmental grant and by core grant P30 EY010572 from the NIH. Lee Kiang, MD, PhD, is a fellow of the Heed Ophthalmic Foundation. The authors report no relevant financial disclosures. Address correspondence to Phoebe Lin, MD, PhD, Assistant Professor of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, 3375 SW Terwilliger Blvd., Portland, OR 97239; email: linp@ohsu.edu. doi: 10.3928/23258160-20170802-13

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N2 - A 78-year-old immunocompetent man presented with a 3-month history of painless decreased vision and panuveitis with a macular lesion presumed to be due to endogenous endophthalmitis. He had been treated with systemic, intravenous, and intravitreal antibiotics and antifungal agents as well as intravitreal steroids. A culture from a prior vitrectomy had grown a single colony of Aspergillus thought to be a contaminant. The macular lesion enlarged and caused a tractional retinal detachment. The patient underwent surgery including resection of what appeared to be an invasive retinal aspergilloma, from which polymerase chain reaction and histopathology confirmed Aspergillus fumigatus.

AB - A 78-year-old immunocompetent man presented with a 3-month history of painless decreased vision and panuveitis with a macular lesion presumed to be due to endogenous endophthalmitis. He had been treated with systemic, intravenous, and intravitreal antibiotics and antifungal agents as well as intravitreal steroids. A culture from a prior vitrectomy had grown a single colony of Aspergillus thought to be a contaminant. The macular lesion enlarged and caused a tractional retinal detachment. The patient underwent surgery including resection of what appeared to be an invasive retinal aspergilloma, from which polymerase chain reaction and histopathology confirmed Aspergillus fumigatus.

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Aspergillus endophthalmitis resulting in development of retinal aspergilloma

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