Abstract
This narrative review appraises the human and animal studies implicating ascorbic acid (AA) in normal cognitive function and Alzheimer's disease. A research framework for how nutrition affects brain aging is proposed with emphasis on AA intake, status, metabolism, and transport into brain tissue. A final synopsis highlights areas for future research regarding AA nourishment and healthy brain aging.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 114-122 |
| Number of pages | 9 |
| Journal | BioFactors |
| Volume | 38 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 2012 |
| Externally published | Yes |
Keywords
- Alzheimer's disease
- Ascorbic acid
- Blood-CSF barrier
- Blood-brain barrier
- CSF
- Choroid plexus
- Cognitive function
- Dementia
- Plasma
- SVCT
- Vitamin C
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Clinical Biochemistry