Are untimed antiretroviral drug levels useful predictors of adherence behavior?

Cheryl A. Liechty, Christopher S. Alexander, P. Richard Harrigan, J. David Guzman, Edwin D. Charlebois, Andrew R. Moss, David R. Bangsberg

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

We examined cross-sectionally the relationship between untimed drug levels and adherence in 83 individuals. Abnormally low untimed antiretroviral drug levels were sensitive in identifying individuals adherent to 60% or less of medication doses over a 3-5-week period. An abnormally low drug level was associated with a higher viral load. A single abnormally low untimed antiretroviral drug level can identify an individual with very low adherence at high risk of HIV disease progression and death.

Original languageEnglish (US)
Pages (from-to)127-129
Number of pages3
JournalAIDS
Volume18
Issue number1
DOIs
StatePublished - Jan 2 2004
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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