Appropriate use of beta blockers in cirrhosis

Ranjan Mascarenhas, Atif Zaman

Research output: Contribution to journalArticle

Abstract

Cirrhosis of the liver from various etiologies is a leading cause of morbidity and mortality in developing countries and industrialized nations alike. Beta blockers have been used for primary and secondary prophylaxis to prevent the initial episode of bleeding as well as rebleeding from gastroesophageal varices for several decades. However, the side effects of nonselective beta blockers preclude their use in all patients with cirrhosis. Recent evidence suggests that the use of beta blockers in patients with decompensated cirrhosis and refractory ascites may be contraindicated. The purpose of this review is to describe the appropriate use of beta blockers in cirrhosis taking into account emerging data.

Original languageEnglish (US)
Pages (from-to)243-249
Number of pages7
JournalCurrent Hepatitis Reports
Volume14
Issue number3
DOIs
StatePublished - Jul 15 2015

Keywords

  • Beta blocker
  • Cirrhosis
  • Portal hypertension
  • Refractory ascites
  • Varices

ASJC Scopus subject areas

  • Hepatology
  • Virology

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