Application of GRADE in systematic reviews: Necessity, frequently-asked questions and concerns

Yao Long Chen, Liang Yao, Norris Susan, Liang Du, Hao Chen, Xian Tao Zeng, Zhi Mao, Ke Hu Yang

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We elaborated the reasons why systematic reviews need to use GRADE based on a couple of specific examples. Aiming to provide references to understand and use GRADE correctly, we also answered some frequently-asked questions and concerns about GRADE as follows: a) differentiating the uses of GRADE between its application in guidelines and in systematic reviews; b) how to determine the overall quality of evidence? c) can GRADE be used to access the quality of single study or not? d) different uses of GRADE between randomized controlled trials (RCTs) and observational studies; e) weight of GRADE items; and f) factors that might influence the results of GRADE and the balance between upgrading and downgrading.

Original languageEnglish (US)
Pages (from-to)1401-1404
Number of pages4
JournalChinese Journal of Evidence-Based Medicine
Volume13
Issue number12
DOIs
StatePublished - 2013
Externally publishedYes

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Observational Studies
Randomized Controlled Trials
Guidelines
Weights and Measures

Keywords

  • GRADE
  • Grading Evidence
  • Systematic review

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Application of GRADE in systematic reviews : Necessity, frequently-asked questions and concerns. / Chen, Yao Long; Yao, Liang; Susan, Norris; Du, Liang; Chen, Hao; Zeng, Xian Tao; Mao, Zhi; Yang, Ke Hu.

In: Chinese Journal of Evidence-Based Medicine, Vol. 13, No. 12, 2013, p. 1401-1404.

Research output: Contribution to journalArticle

Chen, Yao Long ; Yao, Liang ; Susan, Norris ; Du, Liang ; Chen, Hao ; Zeng, Xian Tao ; Mao, Zhi ; Yang, Ke Hu. / Application of GRADE in systematic reviews : Necessity, frequently-asked questions and concerns. In: Chinese Journal of Evidence-Based Medicine. 2013 ; Vol. 13, No. 12. pp. 1401-1404.
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