Aortic, pulmonary, and ductal peak velocities in symmetrical and asymmetrical fetal growth retardation: A different adaptation to placental insufficiency

M. Bellotti, E. Ferrazzi, A. Barbera, G. D'Orta, G. Pardi, Kent Thornburg

    Research output: Contribution to journalArticle

    Abstract

    Objective: The objective of this study was to investigate the peak velocities of the outflow tract of the great vessels in symmetrical and asymmetrical growth-retarded fetuses. Methods: Aortic, pulmonary artery, and ductal peak velocities and the pulsatility index (PI) of the umbilical artery and of the middle cerebral artery (MCA) were measured by Doppler velocimetry in 31 symmetrically and 48 asymmetrically growth-retarded fetuses within 3 days before delivery. Results: In the symmetrical intrauterine growth retarded (IUGR) fetuses, the peak velocities were not significantly lower than in normal fetuses of comparable weight. In the asymmetrical IUGR fetuses, peak velocities were significantly lower than in normal fetuses (aorta, P <0.001; pulmonary artery, P <0.03; ductus arteriosus, P <0.003). The PI of the MCA in the asymmetrical IUGR fetuses was significantly lower than that in the symmetrical IUGR fetuses. Twenty of 37 elective cesarean sections were performed for fetal distress in the asymmetrical group. Intrauterine deaths occurred only in the asymmetrical group with abnormal peak velocities. Conclusion: This study presents evidence that, in asymmetrical IUGR fetuses, the long-standing flow redistribution is associated with a significantly higher risk of impaired ejection velocities from the left and right ventricles and intrauterine distress.

    Original languageEnglish (US)
    Pages (from-to)35-39
    Number of pages5
    JournalJournal of Maternal-Fetal Investigation
    Volume6
    Issue number1
    StatePublished - 1996

    Fingerprint

    Placental Insufficiency
    Fetal Growth Retardation
    Fetus
    Lung
    Growth
    Middle Cerebral Artery
    Pulmonary Artery
    Heart Ventricles
    Ductus Arteriosus
    Fetal Distress
    Umbilical Arteries
    Rheology
    Cesarean Section
    Aorta
    Weights and Measures

    Keywords

    • Doppler ultrasonography
    • Echocardiography
    • Fetal heart
    • Intrauterine growth retardation

    ASJC Scopus subject areas

    • Obstetrics and Gynecology

    Cite this

    Aortic, pulmonary, and ductal peak velocities in symmetrical and asymmetrical fetal growth retardation : A different adaptation to placental insufficiency. / Bellotti, M.; Ferrazzi, E.; Barbera, A.; D'Orta, G.; Pardi, G.; Thornburg, Kent.

    In: Journal of Maternal-Fetal Investigation, Vol. 6, No. 1, 1996, p. 35-39.

    Research output: Contribution to journalArticle

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    T1 - Aortic, pulmonary, and ductal peak velocities in symmetrical and asymmetrical fetal growth retardation

    T2 - A different adaptation to placental insufficiency

    AU - Bellotti, M.

    AU - Ferrazzi, E.

    AU - Barbera, A.

    AU - D'Orta, G.

    AU - Pardi, G.

    AU - Thornburg, Kent

    PY - 1996

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