@inproceedings{f33d49057c474bb5a2b7979e4eeb46a1,
title = "AO-OCT for in vivo mouse retinal imaging: Application of adaptive lens in wavefornt sensorless aberration correction",
abstract = "We demonstrate Adaptive optics - Optical Coherence Tomography (OCT) with modal sensorless Adaptive Optics correction with the use of novel Adaptive Lens (AL) applied for in-vivo imaging of mouse retinas. The AL can generate low order aberrations: defocus, astigmatism, coma and spherical aberration that were used in an adaptive search algorithm. Accelerated processing of the OCT data with a Graphic Processing Unit (GPU) permitted real time extraction of image projection total intensity for arbitrarily selected retinal depth plane to be optimized. Wavefront sensorless control is a viable option for imaging biological structures for which AOOCT cannot establish a reliable wavefront that could be corrected by wavefront corrector. Image quality improvements offered by adaptive lens with sensorless AO-OCT was evaluated on in vitro samples followed by mouse retina data acquired in vivo.",
keywords = "Aberration compensation, Adaptive optics, Imaging system, Optical coherence tomography",
author = "Stefano Bonora and Yifan Jian and Pugh, {Edward N.} and Sarunic, {Marinko V.} and Zawadzki, {Robert J.}",
year = "2013",
doi = "10.1117/12.2042018",
language = "English (US)",
isbn = "9780819498472",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
booktitle = "Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII",
note = "Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII ; Conference date: 03-02-2014 Through 05-02-2014",
}