Antitrichomonas IgG, IgM, IgA, and IgG subclass responses in human intravaginal trichomoniasis

Simernjeet Kaur, Sumeeta Khurana, Rashmi Bagga, Ajay Wanchu, Nancy Malla

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Abstract

Trichomoniasis, caused by the protozoan parasite Trichomonas vaginalis, is a major nonviral sexually transmitted disease. Clinical spectrum varies from an asymptomatic state to mild, moderate, or severe symptoms. However, the exact factors leading to the variations in symptoms have not been well elucidated. Host's immune response to the parasite may be playing a role in varied symptomatology. The present study reports antitrichomonas IgM, IgA, IgG and its subclasses in doubling dilutions of serum and diluted vaginal washes of six T. vaginalis-infected symptomatic and four T. vaginalis-infected asymptomatic women and uninfected controls by enzyme-linked immunosorbent assay (ELISA). No significant difference was observed in serum IgG ELISA absorbance values from symptomatic compared to asymptomatic subjects (p>0.05) while a significant difference (p

Original languageEnglish (US)
Pages (from-to)305-312
Number of pages8
JournalParasitology Research
Volume103
Issue number2
DOIs
Publication statusPublished - Jul 2008
Externally publishedYes

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ASJC Scopus subject areas

  • Parasitology

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