Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro

Dennis N. Bourdette, Fredrick J. Seil, John W. Bigbee, George H. DeVries, Margaret M. Garwood, Harish C. Agrawal

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Antisera prepared to an axolemma-enriched fraction derived from rat brain inhibited neurite outgrowth and destroyed mature axons in spinal cord-dorsal root ganglia cultures. Similar antibody-mediated anti-axon effects may be important in some diseases of the human nervous system.

Original languageEnglish (US)
Pages (from-to)333-337
Number of pages5
JournalBrain research
Volume366
Issue number1-2
DOIs
StatePublished - Feb 26 1986

Keywords

  • anti-axolemma antibody
  • anti-axon antibody
  • axolemma
  • neural tissue culture

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint Dive into the research topics of 'Antisera to an axolemma-enriched fraction inhibit neurite outgrowth and destroy axons in vitro'. Together they form a unique fingerprint.

  • Cite this