@article{44d62fd065024963b40fdc463e4009bf,
title = "Antisera to an Axolemma‐Enriched Fraction Have Antiaxon and Antimyelin Effects in Vitro",
author = "BOURDETTE, {DENNIS N.} and SEIL, {FREDRICK J.} and MESHUL, {CHARLES K.} and BIGBEE, {JOHN W.} and DeVRIES, {GEORGE H.} and AGRAWAL, {HARISH C.}",
note = "Funding Information: Supported by the Veterans Administration and by NIH grants NS13464, NS19414, NSIO821, and NS15408. Funding Information: 2 second, high intensity sound (Ii0 db at 2900 hz, VI-I min.) 2 hours daily for 4 days. The femurs and tibias were dissected from the animals, bone marrow cells separated and suspended in media. In vitro migration assays were employed using blind well chambers. Thymus supernatant from 3 day old mice was used as the attractant in the bottom well separated from the bone marrow cells in the top well by Nucleopore membranes having 5 ~m diameter pores. After 90 minutes incubation, cells migrating to the bottom chamber were collected, counted and compared to controls. Preliminary studies suggest a measurable increase in the number of migrating bone marrow cells in the stressed females suggesting that acute stress may enhance pre-thymic stem cell production in the bone marrow. Future studies will evaluate the effects of acute versus chronic stress on pre-thymic cell populations. (Supported by NIH grant AG 04384)",
year = "1988",
month = nov,
doi = "10.1111/j.1749-6632.1988.tb27122.x",
language = "English (US)",
volume = "540",
pages = "423--426",
journal = "Annals of the New York Academy of Sciences",
issn = "0077-8923",
publisher = "Wiley-Blackwell",
number = "1",
}