Antimicrobial prescribing practices in response to different Clostridium difficile diagnostic methodologies

Emily R.M. Sydnor; Abigail Lenhart; Brandon Trollinger; Edina Avdic; Lisa L. Maragakis; Karen C. Carroll; Sara E. Cosgrove

doi:10.1086/662381

Antimicrobial prescribing practices in response to different Clostridium difficile diagnostic methodologies

Emily R.M. Sydnor, Abigail Lenhart, Brandon Trollinger, Edina Avdic, Lisa L. Maragakis, Karen C. Carroll, Sara E. Cosgrove

Department of Medicine

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

We evaluated treatment decisions and antimicrobial use related to 2 testing algorithms for Clostridium difficile infection (CDI). Our findings suggest that a 2-step testing algorithm using rapid polymerase chain reaction confirmatory testing leads to decreased unnecessary anti-CDI antimicrobial use. In addition, a significant proportion of patients with confirmed CDI were not treated according to recommended guidelines.

Original language	English (US)
Pages (from-to)	1133-1136
Number of pages	4
Journal	Infection control and hospital epidemiology
Volume	32
Issue number	11
DOIs	https://doi.org/10.1086/662381
State	Published - Nov 2011

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.1086/662381

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abstract = "We evaluated treatment decisions and antimicrobial use related to 2 testing algorithms for Clostridium difficile infection (CDI). Our findings suggest that a 2-step testing algorithm using rapid polymerase chain reaction confirmatory testing leads to decreased unnecessary anti-CDI antimicrobial use. In addition, a significant proportion of patients with confirmed CDI were not treated according to recommended guidelines.",

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AU - Carroll, Karen C.

AU - Cosgrove, Sara E.

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AB - We evaluated treatment decisions and antimicrobial use related to 2 testing algorithms for Clostridium difficile infection (CDI). Our findings suggest that a 2-step testing algorithm using rapid polymerase chain reaction confirmatory testing leads to decreased unnecessary anti-CDI antimicrobial use. In addition, a significant proportion of patients with confirmed CDI were not treated according to recommended guidelines.

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Antimicrobial prescribing practices in response to different Clostridium difficile diagnostic methodologies

Abstract

ASJC Scopus subject areas

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