Anthropology of the apolipoprotein e (apo E) gene: Low frequency of apo E4 allele in Basques and in tribal (Baiga) populations of India

S. S. Mastana, R. Calderon, J. Pena, P. H. Reddy, S. S. Papiha

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

The distribution of apolipoprotein E (apo E) polymorphism was examined in 11 population groups not previously studied for this system. There is a marked difference in phenotype and gene frequency between the populations of England and Spain. The south European populations of Basques and Spanish non-Basques showed greater similarity to the populations of South Asia. The study clearly indicates that the distribution of apo E alleles does match with regions showing a high mortality rate of coronary heart disease. The data presented also indicate that authochthon groups such as Basques in Europe and tribals in India may throw better light on the role of apolipoproteins in the regulation of lipid levels in disease.

Original languageEnglish (US)
Pages (from-to)137-143
Number of pages7
JournalAnnals of Human Biology
Volume25
Issue number2
DOIs
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Epidemiology
  • Physiology
  • Aging
  • Genetics
  • Public Health, Environmental and Occupational Health

Fingerprint

Dive into the research topics of 'Anthropology of the apolipoprotein e (apo E) gene: Low frequency of apo E4 allele in Basques and in tribal (Baiga) populations of India'. Together they form a unique fingerprint.

Cite this