Anthropology of the apolipoprotein e (apo E) gene

Low frequency of apo E4 allele in Basques and in tribal (Baiga) populations of India

S. S. Mastana, R. Calderon, J. Pena, P (Hemachandra) Reddy, S. S. Papiha

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The distribution of apolipoprotein E (apo E) polymorphism was examined in 11 population groups not previously studied for this system. There is a marked difference in phenotype and gene frequency between the populations of England and Spain. The south European populations of Basques and Spanish non-Basques showed greater similarity to the populations of South Asia. The study clearly indicates that the distribution of apo E alleles does match with regions showing a high mortality rate of coronary heart disease. The data presented also indicate that authochthon groups such as Basques in Europe and tribals in India may throw better light on the role of apolipoproteins in the regulation of lipid levels in disease.

Original languageEnglish (US)
Pages (from-to)137-143
Number of pages7
JournalAnnals of Human Biology
Volume25
Issue number2
StatePublished - Mar 1998
Externally publishedYes

Fingerprint

Apolipoprotein E4
anthropology
apolipoproteins
Anthropology
Apolipoproteins
Gene Frequency
India
Alleles
alleles
Population
genes
Apolipoproteins E
Population Groups
England
apolipoprotein E
Spain
Coronary Disease
South Asia
gene frequency
Phenotype

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Public Health, Environmental and Occupational Health

Cite this

Anthropology of the apolipoprotein e (apo E) gene : Low frequency of apo E4 allele in Basques and in tribal (Baiga) populations of India. / Mastana, S. S.; Calderon, R.; Pena, J.; Reddy, P (Hemachandra); Papiha, S. S.

In: Annals of Human Biology, Vol. 25, No. 2, 03.1998, p. 137-143.

Research output: Contribution to journalArticle

Mastana, S. S. ; Calderon, R. ; Pena, J. ; Reddy, P (Hemachandra) ; Papiha, S. S. / Anthropology of the apolipoprotein e (apo E) gene : Low frequency of apo E4 allele in Basques and in tribal (Baiga) populations of India. In: Annals of Human Biology. 1998 ; Vol. 25, No. 2. pp. 137-143.
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