Anterior Uveitis following COVID Vaccination: A Summary of Cases from Global Reporting Systems

Afshan A. Nanji, Frederick T. Fraunfelder

Research output: Contribution to journalLetterpeer-review

7 Scopus citations

Abstract

Purpose: COVID-19 vaccines are currently undergoing long-term safety monitoring, including for ocular side effects. Uveitis following vaccination has been described previously with other vaccines and warrants evaluation for COVID-19 vaccines, especially given their widespread use. Case Reports: We present two cases of patients who developed anterior uveitis following the Moderna COVID-19 vaccine, as reported to the National Registry for Drug-Induced Ocular Side Effects. We also summarize reports of anterior uveitis following COVID-19 vaccination as reported to the World Health Organization global database of individual case safety reports. Conclusions: Based on the temporal pattern of ocular inflammation following vaccine delivery in these cases, an association may be present between uveitis and COVID-19 vaccination. Further investigation to explore this association is warranted to guide patient care.

Original languageEnglish (US)
Pages (from-to)1244-1246
Number of pages3
JournalOcular Immunology and Inflammation
Volume30
Issue number5
DOIs
StatePublished - 2022

Keywords

  • COVID-19
  • National Registry of Drug-Induced Ocular Side Effects
  • Uppsala Monitoring Center
  • anterior uveitis
  • vaccine

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology

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