Anterior Uveitis following COVID Vaccination: A Summary of Cases from Global Reporting Systems

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1 Scopus citations

Abstract

Purpose: COVID-19 vaccines are currently undergoing long-term safety monitoring, including for ocular side effects. Uveitis following vaccination has been described previously with other vaccines and warrants evaluation for COVID-19 vaccines, especially given their widespread use. Case Reports: We present two cases of patients who developed anterior uveitis following the Moderna COVID-19 vaccine, as reported to the National Registry for Drug-Induced Ocular Side Effects. We also summarize reports of anterior uveitis following COVID-19 vaccination as reported to the World Health Organization global database of individual case safety reports. Conclusions: Based on the temporal pattern of ocular inflammation following vaccine delivery in these cases, an association may be present between uveitis and COVID-19 vaccination. Further investigation to explore this association is warranted to guide patient care.

Original languageEnglish (US)
JournalOcular Immunology and Inflammation
DOIs
StateAccepted/In press - 2022
Externally publishedYes

Keywords

  • anterior uveitis
  • COVID-19
  • National Registry of Drug-Induced Ocular Side Effects
  • Uppsala Monitoring Center
  • vaccine

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology

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