Antecedents of global decline in health-related quality of life among middle-aged African Americans

Fredric D. Wolinsky, Theodore K. Malmstrom, J. Philip Miller, Elena Andresen, Mario Schootman, Douglas K. Miller

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objective We examined global declines in health-related quality of life (HRQoL) for a period of 3 years among the 998 participants in the African American Health (AAH) project.MethodsThe AAH is a population-based sample from two areas of metropolitan St. Louis. Global declines were defined as clinically important differences (CIDs) on four or more of the eight Short Form 36-Item scales. Individual CIDs were defined as drops of 0.5 SD or more from the baseline score. Multivariable logistic regression was used to identify antecedents of global decline.ResultsFourteen percent (n = 117) of the 846 AAH subjects in the analysis demonstrated global declines in HRQoL. Five statistically significant risk factors were identified, including sampling strata (inner-city vs. suburban residence; adjusted odds ratio [AOR] = 2.06), cancer (AOR = 3.56), chronic obstructive pulmonary disease (AOR = 2.19), clinically relevant levels of depressive symptoms (AOR = 1.96), and incident (postbaseline) health conditions (1 [AOR = 1.71] and ≥2 [AOR = 3.09] vs. none).ConclusionAlthough these risk factors are for the most part nonmalleable, they can serve as markers of impending global HRQoL declines among late-middle-aged African Americans.

Original languageEnglish (US)
Pages (from-to)290-295
Number of pages6
JournalJournals of Gerontology - Series B Psychological Sciences and Social Sciences
Volume64
Issue number2
DOIs
StatePublished - Mar 2009
Externally publishedYes

Fingerprint

African Americans
quality of life
Odds Ratio
Quality of Life
health
Health
Chronic Obstructive Pulmonary Disease
social stratum
American
Logistic Models
incident
Depression
cancer
logistics
Disease
regression
Population
Neoplasms

Keywords

  • African Americans
  • Epidemiology
  • Health-related quality of life
  • Prospective cohort study

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Gerontology
  • Clinical Psychology
  • Social Psychology
  • Medicine(all)

Cite this

Antecedents of global decline in health-related quality of life among middle-aged African Americans. / Wolinsky, Fredric D.; Malmstrom, Theodore K.; Miller, J. Philip; Andresen, Elena; Schootman, Mario; Miller, Douglas K.

In: Journals of Gerontology - Series B Psychological Sciences and Social Sciences, Vol. 64, No. 2, 03.2009, p. 290-295.

Research output: Contribution to journalArticle

Wolinsky, Fredric D. ; Malmstrom, Theodore K. ; Miller, J. Philip ; Andresen, Elena ; Schootman, Mario ; Miller, Douglas K. / Antecedents of global decline in health-related quality of life among middle-aged African Americans. In: Journals of Gerontology - Series B Psychological Sciences and Social Sciences. 2009 ; Vol. 64, No. 2. pp. 290-295.
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