Angiotensin-converting enzyme and cardiovascular disease risk

Jean Pruss O'Malley, Cheryl Maslen, D. Roger Illingworth

    Research output: Contribution to journalArticle

    23 Citations (Scopus)

    Abstract

    The published studies of the association of the angiotensin-converting enzyme (ACE) genotype with cardiovascular disease have used many different diagnostic criteria for cardiovascular disease and have drawn their samples from different patient groups and different populations. This review examines the association of the ACE DD genotype with cardiovascular disease risk in studies grouped by their case criterion, the geographical region of the population samples, and by the cardiovascular risk level of the patient sample. In studies where the underlying odds ratios are determined to be homogeneous, the overall odds ratios for myocardial infarction and coronary artery disease with regard to the ACE DD genotype are estimated using the Mantel-Haenszel method.

    Original languageEnglish (US)
    Pages (from-to)407-415
    Number of pages9
    JournalCurrent Opinion in Lipidology
    Volume10
    Issue number5
    DOIs
    StatePublished - 1999

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    Peptidyl-Dipeptidase A
    Cardiovascular Diseases
    Genotype
    Odds Ratio
    Geographical regions
    Population Groups
    Population

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

    Cite this

    Angiotensin-converting enzyme and cardiovascular disease risk. / O'Malley, Jean Pruss; Maslen, Cheryl; Illingworth, D. Roger.

    In: Current Opinion in Lipidology, Vol. 10, No. 5, 1999, p. 407-415.

    Research output: Contribution to journalArticle

    O'Malley, Jean Pruss ; Maslen, Cheryl ; Illingworth, D. Roger. / Angiotensin-converting enzyme and cardiovascular disease risk. In: Current Opinion in Lipidology. 1999 ; Vol. 10, No. 5. pp. 407-415.
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