Angiolymphoid hyperplasia with eosinophilia of the orbit and ocular adnexa report of 5 cases

Amir A. Azari, Mozhgan R. Kanavi, Mark Lucarelli, Vivian Lee, Ashley M. Lundin, Heather D. Potter, Daniel M. Albert

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


OBSERVATIONS The ophthalmologic findings of angiolymphoid hyperplasia with eosinophilia with ocular adnexal involvement are variable and include eyelid swelling, ptosis, proptosis, and loss of vision. Imaging studies typically reveal a well-circumscribed mass in the orbit. The condition may resemble other diseases that involve the orbit and ocular adnexal tissue, such as lymphoma, hemangioma, sarcoidosis, and dermoid cyst. Histopathologic analysis reveals marked vascular proliferation with an accompanying inflammation composed of numerous eosinophils, lymphocytes, and plasma cells. CONCLUSIONS AND RELEVANCE Angiolymphoid hyperplasia with eosinophilia is a rare disease that can affect the ocular adnexal tissue. The clinical presentation is often nonspecific; therefore, histopathologic studies are essential for diagnosis and subsequent management of this benign condition.

Original languageEnglish (US)
Pages (from-to)633-636
Number of pages4
JournalJAMA ophthalmology
Issue number5
StatePublished - May 2014
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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