Angiographic findings in mixed connective tissue disease. Correlation with fingernail capillary photomicroscopy and digital photoplethysmography findings

Jeffrey S. Peller, Gary T. Gabor, John M. Porter, Robert M. Bennett

    Research output: Contribution to journalArticle

    16 Scopus citations

    Abstract

    Thirteen patients with mixed connective tissue disease underwent hand angiography to assess the degree of vascular abnormalities and their correlation to nailfold capillary microscopy and digital photoplethysmography findings. Organic obstruction was found in 60% of ulnar arteries, 87% of superficial arches, 13% of deep arches, and 65% of digital arteries. Fingernail capillary abnormalities were seen in 90% of patients. Normal photoplethysmography results had a predictive value of 91% for identifying digits without bilateral occlusions. These findings indicate a hitherto unrecognized propensity for disease of both small and medium‐sized vessels in patients with mixed connective tissue disease.

    Original languageEnglish (US)
    Pages (from-to)768-774
    Number of pages7
    JournalArthritis & Rheumatism
    Volume28
    Issue number7
    DOIs
    StatePublished - Jul 1985

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    ASJC Scopus subject areas

    • Immunology and Allergy
    • Rheumatology
    • Immunology
    • Pharmacology (medical)

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