Angiocentric T-cell lymphoma presenting as midface destructive lesion: Case report and literature review

Yung Yih Wei, Jeffery C.B. Stewart, F. James Kratochvil, Monica B. Zieper

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A case of angiocentric T-cell lymphoma presenting as a midface destructive lesion is reported. Angiocentric T-cell lymphoma typically manifests as an aggressive, progressively destructive, and necrotizing disorder, often with a fatal outcome. This case was characterized microscopically by the presence of an atypical lymphoid population that expressed a CD45+, CD3+ cytoplasmic, CD5+, and CD56- T-cell phenotype within a background of a polymorphous inflammatory infiltrate. Because of the rarity of the disorder, the differential diagnosis is discussed. Recent advances in clinical immunodiagnostics, the variations in therapeutic modalities, and the prognosis of the disease as reported in the recent literature are reviewed.

Original languageEnglish (US)
Pages (from-to)353-360
Number of pages8
JournalOral surgery, oral medicine, oral pathology, oral radiology, and endodontics
Volume94
Issue number3
DOIs
StatePublished - 2002
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology
  • General Dentistry

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