Anesthetic agents and sympatho-adrenal response to hemorrhage in the rat

B. Hamberger, L. Bengtsson, Per-Olof Järnberg, L. O. Farnebo

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The sympatho-adrenal activity as reflected in plasma catecholamine levels was studied in rats subjected to a standardized hemorrhage. A comparison was performed between awake rats and rats anesthetized with diethylether, enflurane, barbiturate or ketamine. As expected diethylether increased sympathoadrenal activity. Enflurane induction increased adrenaline and decreased noradrenaline levels. Upon hemorrhage the sympathoadrenal activity was depressed compared to the awake state. Barbiturate anesthesia depressed sympatho-adrenal activity. Ketamine increased noradrenaline levels and a relative hypertension was noticed during bleeding. The results focuse attention on important differences in sympatho-adrenal activity between awake rats and rats anesthetized with different agents.

Original languageEnglish (US)
Pages (from-to)109-113
Number of pages5
JournalActa Chirurgica Scandinavica
Volume150
Issue numberSUPPL. 520
StatePublished - 1984
Externally publishedYes

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Anesthetics
Hemorrhage
Enflurane
Ketamine
Norepinephrine
Epinephrine
Catecholamines
Anesthesia
Hypertension
barbituric acid

ASJC Scopus subject areas

  • Surgery

Cite this

Hamberger, B., Bengtsson, L., Järnberg, P-O., & Farnebo, L. O. (1984). Anesthetic agents and sympatho-adrenal response to hemorrhage in the rat. Acta Chirurgica Scandinavica, 150(SUPPL. 520), 109-113.

Anesthetic agents and sympatho-adrenal response to hemorrhage in the rat. / Hamberger, B.; Bengtsson, L.; Järnberg, Per-Olof; Farnebo, L. O.

In: Acta Chirurgica Scandinavica, Vol. 150, No. SUPPL. 520, 1984, p. 109-113.

Research output: Contribution to journalArticle

Hamberger, B, Bengtsson, L, Järnberg, P-O & Farnebo, LO 1984, 'Anesthetic agents and sympatho-adrenal response to hemorrhage in the rat', Acta Chirurgica Scandinavica, vol. 150, no. SUPPL. 520, pp. 109-113.
Hamberger B, Bengtsson L, Järnberg P-O, Farnebo LO. Anesthetic agents and sympatho-adrenal response to hemorrhage in the rat. Acta Chirurgica Scandinavica. 1984;150(SUPPL. 520):109-113.
Hamberger, B. ; Bengtsson, L. ; Järnberg, Per-Olof ; Farnebo, L. O. / Anesthetic agents and sympatho-adrenal response to hemorrhage in the rat. In: Acta Chirurgica Scandinavica. 1984 ; Vol. 150, No. SUPPL. 520. pp. 109-113.
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