Anemia: Evaluation and Diagnostic Tests

Michael J. Cascio, Thomas G. DeLoughery

Research output: Contribution to journalReview articlepeer-review

42 Scopus citations


Anemia is among the most common medical problems and clinical and laboratory evaluation need to be approached logically. The complete blood count with red cell indices offers clues to diagnosis. Many anemias have characteristic red cell morphology. The reticulocyte count serves as a useful screen for hemolysis or blood loss. Testing for specific causes of the anemia is performed. Occasionally, examination of the bone marrow is required for diagnosis. Molecular testing is increasingly being use to aid the diagnostic process. This article reviews diagnostic tests for anemia and suggests a rational approach to determining the etiology of a patient's anemia.

Original languageEnglish (US)
Pages (from-to)263-284
Number of pages22
JournalMedical Clinics of North America
Issue number2
StatePublished - Mar 1 2017


  • Anemia
  • Cytogenetics
  • Diagnostic testing
  • Macrocytic
  • Microcytic
  • Red cell indices
  • Schistocytes

ASJC Scopus subject areas

  • Medicine(all)


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