Anatomically Oriented Right Ventricular Volume Measurements With Dynamic Three-Dimensional Echocardiography Validated by 3-Tesla Magnetic Resonance Imaging

Petra S. Niemann, Luiz Pinho, Thomas Balbach, Christian Galuschky, Michael Blankenhagen, Gary (Michael) Silberbach, Craig Broberg, Michael Jerosch-Herold, David Sahn

Research output: Contribution to journalArticle

176 Citations (Scopus)

Abstract

Objectives: We tested a newly developed 4-dimensional (4D) right ventricular (RV) analysis method for computing RV volumes for both 3-dimensional (3D) ultrasound (US) and magnetic resonance (MR) images. Background: Asymmetry and the anatomical complexity of the RV make accurate determination of RV shape and volume difficult. Methods: Thirty patients, 14 with grossly normal cardiac anatomy and 16 with major congenital heart disease, were studied at the same visit with both 3D echocardiography (echo) and magnetic resonance imaging (MRI) for RV size and function. Ultrasound images were acquired on a Philips 7500 system (Philips Medical Systems, Andover, Massachusetts) with a matrix-array transducer (real-time 3D echo) with full volume sweeps from apical and subcostal views. Sagittal, 4-chamber, and coronal views were derived for contour detection (all 12 to 24 slices). The MR images were acquired with a 3-T MRI magnet with segmented cine-loop gradient echo sequences in short- and rotated long-axis views to cover the RV inflow, body, and outflow tract. The RV volumes were analyzed with the new software applicable to 3D echo MR images. Results: New software aided delineation of the RV free wall, tricuspid valve, RV outflow tract, and apex on 3D echo volumes. Although there was a slightly higher variability measuring right ventricular ejection fraction (RVEF) and volumes obtained by US compared with MRI, both imaging methods showed closely correlated results. The RVEF was measured with 4% variability for US and 5% variability for MRI with a correlation coefficient of r = 0.91. The RV end-diastolic volume was measured at 70.97 ± 15.0 ml with 3D US and at 70.06 ± 14.8 ml with MRI (r = 0.99), end-systolic volume measured 39.8 ± 10.4 ml with 3D US and 39.1 ± 10.2 ml with MRI (r = 0.98). Conclusions: The new RV analysis software allowed validation of the accuracy of 4D echo RV volume data compared with MRI.

Original languageEnglish (US)
Pages (from-to)1668-1676
Number of pages9
JournalJournal of the American College of Cardiology
Volume50
Issue number17
DOIs
StatePublished - Oct 23 2007

Fingerprint

Three-Dimensional Echocardiography
Echocardiography
Magnetic Resonance Imaging
Stroke Volume
Magnetic Resonance Spectroscopy
Software Validation
Software
Right Ventricular Function
Tricuspid Valve
Magnets
Transducers
Heart Diseases
Anatomy

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Anatomically Oriented Right Ventricular Volume Measurements With Dynamic Three-Dimensional Echocardiography Validated by 3-Tesla Magnetic Resonance Imaging. / Niemann, Petra S.; Pinho, Luiz; Balbach, Thomas; Galuschky, Christian; Blankenhagen, Michael; Silberbach, Gary (Michael); Broberg, Craig; Jerosch-Herold, Michael; Sahn, David.

In: Journal of the American College of Cardiology, Vol. 50, No. 17, 23.10.2007, p. 1668-1676.

Research output: Contribution to journalArticle

Niemann, Petra S. ; Pinho, Luiz ; Balbach, Thomas ; Galuschky, Christian ; Blankenhagen, Michael ; Silberbach, Gary (Michael) ; Broberg, Craig ; Jerosch-Herold, Michael ; Sahn, David. / Anatomically Oriented Right Ventricular Volume Measurements With Dynamic Three-Dimensional Echocardiography Validated by 3-Tesla Magnetic Resonance Imaging. In: Journal of the American College of Cardiology. 2007 ; Vol. 50, No. 17. pp. 1668-1676.
@article{39899594a0ee49cc8dfd22a62518eaf8,
title = "Anatomically Oriented Right Ventricular Volume Measurements With Dynamic Three-Dimensional Echocardiography Validated by 3-Tesla Magnetic Resonance Imaging",
abstract = "Objectives: We tested a newly developed 4-dimensional (4D) right ventricular (RV) analysis method for computing RV volumes for both 3-dimensional (3D) ultrasound (US) and magnetic resonance (MR) images. Background: Asymmetry and the anatomical complexity of the RV make accurate determination of RV shape and volume difficult. Methods: Thirty patients, 14 with grossly normal cardiac anatomy and 16 with major congenital heart disease, were studied at the same visit with both 3D echocardiography (echo) and magnetic resonance imaging (MRI) for RV size and function. Ultrasound images were acquired on a Philips 7500 system (Philips Medical Systems, Andover, Massachusetts) with a matrix-array transducer (real-time 3D echo) with full volume sweeps from apical and subcostal views. Sagittal, 4-chamber, and coronal views were derived for contour detection (all 12 to 24 slices). The MR images were acquired with a 3-T MRI magnet with segmented cine-loop gradient echo sequences in short- and rotated long-axis views to cover the RV inflow, body, and outflow tract. The RV volumes were analyzed with the new software applicable to 3D echo MR images. Results: New software aided delineation of the RV free wall, tricuspid valve, RV outflow tract, and apex on 3D echo volumes. Although there was a slightly higher variability measuring right ventricular ejection fraction (RVEF) and volumes obtained by US compared with MRI, both imaging methods showed closely correlated results. The RVEF was measured with 4{\%} variability for US and 5{\%} variability for MRI with a correlation coefficient of r = 0.91. The RV end-diastolic volume was measured at 70.97 ± 15.0 ml with 3D US and at 70.06 ± 14.8 ml with MRI (r = 0.99), end-systolic volume measured 39.8 ± 10.4 ml with 3D US and 39.1 ± 10.2 ml with MRI (r = 0.98). Conclusions: The new RV analysis software allowed validation of the accuracy of 4D echo RV volume data compared with MRI.",
author = "Niemann, {Petra S.} and Luiz Pinho and Thomas Balbach and Christian Galuschky and Michael Blankenhagen and Silberbach, {Gary (Michael)} and Craig Broberg and Michael Jerosch-Herold and David Sahn",
year = "2007",
month = "10",
day = "23",
doi = "10.1016/j.jacc.2007.07.031",
language = "English (US)",
volume = "50",
pages = "1668--1676",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Elsevier USA",
number = "17",

}

TY - JOUR

T1 - Anatomically Oriented Right Ventricular Volume Measurements With Dynamic Three-Dimensional Echocardiography Validated by 3-Tesla Magnetic Resonance Imaging

AU - Niemann, Petra S.

AU - Pinho, Luiz

AU - Balbach, Thomas

AU - Galuschky, Christian

AU - Blankenhagen, Michael

AU - Silberbach, Gary (Michael)

AU - Broberg, Craig

AU - Jerosch-Herold, Michael

AU - Sahn, David

PY - 2007/10/23

Y1 - 2007/10/23

N2 - Objectives: We tested a newly developed 4-dimensional (4D) right ventricular (RV) analysis method for computing RV volumes for both 3-dimensional (3D) ultrasound (US) and magnetic resonance (MR) images. Background: Asymmetry and the anatomical complexity of the RV make accurate determination of RV shape and volume difficult. Methods: Thirty patients, 14 with grossly normal cardiac anatomy and 16 with major congenital heart disease, were studied at the same visit with both 3D echocardiography (echo) and magnetic resonance imaging (MRI) for RV size and function. Ultrasound images were acquired on a Philips 7500 system (Philips Medical Systems, Andover, Massachusetts) with a matrix-array transducer (real-time 3D echo) with full volume sweeps from apical and subcostal views. Sagittal, 4-chamber, and coronal views were derived for contour detection (all 12 to 24 slices). The MR images were acquired with a 3-T MRI magnet with segmented cine-loop gradient echo sequences in short- and rotated long-axis views to cover the RV inflow, body, and outflow tract. The RV volumes were analyzed with the new software applicable to 3D echo MR images. Results: New software aided delineation of the RV free wall, tricuspid valve, RV outflow tract, and apex on 3D echo volumes. Although there was a slightly higher variability measuring right ventricular ejection fraction (RVEF) and volumes obtained by US compared with MRI, both imaging methods showed closely correlated results. The RVEF was measured with 4% variability for US and 5% variability for MRI with a correlation coefficient of r = 0.91. The RV end-diastolic volume was measured at 70.97 ± 15.0 ml with 3D US and at 70.06 ± 14.8 ml with MRI (r = 0.99), end-systolic volume measured 39.8 ± 10.4 ml with 3D US and 39.1 ± 10.2 ml with MRI (r = 0.98). Conclusions: The new RV analysis software allowed validation of the accuracy of 4D echo RV volume data compared with MRI.

AB - Objectives: We tested a newly developed 4-dimensional (4D) right ventricular (RV) analysis method for computing RV volumes for both 3-dimensional (3D) ultrasound (US) and magnetic resonance (MR) images. Background: Asymmetry and the anatomical complexity of the RV make accurate determination of RV shape and volume difficult. Methods: Thirty patients, 14 with grossly normal cardiac anatomy and 16 with major congenital heart disease, were studied at the same visit with both 3D echocardiography (echo) and magnetic resonance imaging (MRI) for RV size and function. Ultrasound images were acquired on a Philips 7500 system (Philips Medical Systems, Andover, Massachusetts) with a matrix-array transducer (real-time 3D echo) with full volume sweeps from apical and subcostal views. Sagittal, 4-chamber, and coronal views were derived for contour detection (all 12 to 24 slices). The MR images were acquired with a 3-T MRI magnet with segmented cine-loop gradient echo sequences in short- and rotated long-axis views to cover the RV inflow, body, and outflow tract. The RV volumes were analyzed with the new software applicable to 3D echo MR images. Results: New software aided delineation of the RV free wall, tricuspid valve, RV outflow tract, and apex on 3D echo volumes. Although there was a slightly higher variability measuring right ventricular ejection fraction (RVEF) and volumes obtained by US compared with MRI, both imaging methods showed closely correlated results. The RVEF was measured with 4% variability for US and 5% variability for MRI with a correlation coefficient of r = 0.91. The RV end-diastolic volume was measured at 70.97 ± 15.0 ml with 3D US and at 70.06 ± 14.8 ml with MRI (r = 0.99), end-systolic volume measured 39.8 ± 10.4 ml with 3D US and 39.1 ± 10.2 ml with MRI (r = 0.98). Conclusions: The new RV analysis software allowed validation of the accuracy of 4D echo RV volume data compared with MRI.

UR - http://www.scopus.com/inward/record.url?scp=35248879820&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35248879820&partnerID=8YFLogxK

U2 - 10.1016/j.jacc.2007.07.031

DO - 10.1016/j.jacc.2007.07.031

M3 - Article

C2 - 17950149

AN - SCOPUS:35248879820

VL - 50

SP - 1668

EP - 1676

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

SN - 0735-1097

IS - 17

ER -