Analysis of the insulin gene in noninsulin-dependent diabetes

M. Alan Permutt, Peter Rotwein

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

That diabetes is a metabolic disorder characterized by insulin deficiency is well known. However, the nature and cause of this insulin lack are still to be determined. Recently devised analytical methods, resulting from recombinant DNA technology, have enabled us to study the process of insulin production in man and in experimental animals. The results of these studies suggest that the insulin-secretory defect in diabetes may be secondary to impaired synthesis.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalThe American journal of medicine
Volume75
Issue number5 PART 2
DOIs
StatePublished - Nov 30 1983

Fingerprint

Insulin
Genes
Recombinant DNA
Technology

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Analysis of the insulin gene in noninsulin-dependent diabetes. / Permutt, M. Alan; Rotwein, Peter.

In: The American journal of medicine, Vol. 75, No. 5 PART 2, 30.11.1983, p. 1-7.

Research output: Contribution to journalArticle

Permutt, M. Alan ; Rotwein, Peter. / Analysis of the insulin gene in noninsulin-dependent diabetes. In: The American journal of medicine. 1983 ; Vol. 75, No. 5 PART 2. pp. 1-7.
@article{d2e472f2dcc54b68b26e213c2363db7b,
title = "Analysis of the insulin gene in noninsulin-dependent diabetes",
abstract = "That diabetes is a metabolic disorder characterized by insulin deficiency is well known. However, the nature and cause of this insulin lack are still to be determined. Recently devised analytical methods, resulting from recombinant DNA technology, have enabled us to study the process of insulin production in man and in experimental animals. The results of these studies suggest that the insulin-secretory defect in diabetes may be secondary to impaired synthesis.",
author = "Permutt, {M. Alan} and Peter Rotwein",
year = "1983",
month = "11",
day = "30",
doi = "10.1016/0002-9343(83)90247-4",
language = "English (US)",
volume = "75",
pages = "1--7",
journal = "American Journal of Medicine",
issn = "0002-9343",
publisher = "Elsevier Inc.",
number = "5 PART 2",

}

TY - JOUR

T1 - Analysis of the insulin gene in noninsulin-dependent diabetes

AU - Permutt, M. Alan

AU - Rotwein, Peter

PY - 1983/11/30

Y1 - 1983/11/30

N2 - That diabetes is a metabolic disorder characterized by insulin deficiency is well known. However, the nature and cause of this insulin lack are still to be determined. Recently devised analytical methods, resulting from recombinant DNA technology, have enabled us to study the process of insulin production in man and in experimental animals. The results of these studies suggest that the insulin-secretory defect in diabetes may be secondary to impaired synthesis.

AB - That diabetes is a metabolic disorder characterized by insulin deficiency is well known. However, the nature and cause of this insulin lack are still to be determined. Recently devised analytical methods, resulting from recombinant DNA technology, have enabled us to study the process of insulin production in man and in experimental animals. The results of these studies suggest that the insulin-secretory defect in diabetes may be secondary to impaired synthesis.

UR - http://www.scopus.com/inward/record.url?scp=0021083776&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021083776&partnerID=8YFLogxK

U2 - 10.1016/0002-9343(83)90247-4

DO - 10.1016/0002-9343(83)90247-4

M3 - Article

C2 - 6324584

AN - SCOPUS:0021083776

VL - 75

SP - 1

EP - 7

JO - American Journal of Medicine

JF - American Journal of Medicine

SN - 0002-9343

IS - 5 PART 2

ER -