Analysis of the insulin gene in noninsulin-dependent diabetes

M. Alan Permutt, Peter Rotwein

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Abstract

That diabetes is a metabolic disorder characterized by insulin deficiency is well known. However, the nature and cause of this insulin lack are still to be determined. Recently devised analytical methods, resulting from recombinant DNA technology, have enabled us to study the process of insulin production in man and in experimental animals. The results of these studies suggest that the insulin-secretory defect in diabetes may be secondary to impaired synthesis.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalThe American Journal of Medicine
Volume75
Issue number5 PART 2
DOIs
StatePublished - Nov 30 1983

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ASJC Scopus subject areas

  • Medicine(all)

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