Abstract
Using optical coherence tomography angiography, we measured blood flow from the vessels in the lateral wall in the mouse cochlea directly through bone in mice with and without sympathetic neuronal function. We present in vivo imaging of blood flow and mechanical vibration in mice subjected to 30 min of loud sound. Loud sound caused blood flow reduction. In mice with superior cervical ganglion ablation, the loud sound-induced reduction in blood flow was partially ameliorated. These results demonstrate that sympathetic innervation likely plays a role in the pathological decrease in blood flow observed in the lateral wall vessels in response to loud sound.
| Original language | English (US) |
|---|---|
| Title of host publication | Tenth International Conference on Information Optics and Photonics |
| Editors | Yidong Huang |
| Publisher | SPIE |
| Volume | 10964 |
| ISBN (Electronic) | 9781510625792 |
| DOIs | |
| State | Published - Jan 1 2018 |
| Event | 10th International Conference on Information Optics and Photonics - Beijing, China Duration: Jul 8 2018 → Jul 11 2018 |
Other
| Other | 10th International Conference on Information Optics and Photonics |
|---|---|
| Country | China |
| City | Beijing |
| Period | 7/8/18 → 7/11/18 |
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Keywords
- Blood flow
- Cochlea
- Imaging systems
- Medical optics and biotechnology
- Noiseinduced hearing loss
- Optical coherence tomography
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering
Cite this
Analysis of small vessel cochlear blood flow regulation during loud sound exposure in the mouse. / Burwood, George W.S.; Dziennis, Suzan; Wilson, Teresa; Yang, Jianlong; Liu, Gangjun; Foster, Sarah; Wang, Ruikang; Nuttall, Alfred.
Tenth International Conference on Information Optics and Photonics. ed. / Yidong Huang. Vol. 10964 SPIE, 2018. 109641R.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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TY - GEN
T1 - Analysis of small vessel cochlear blood flow regulation during loud sound exposure in the mouse
AU - Burwood, George W.S.
AU - Dziennis, Suzan
AU - Wilson, Teresa
AU - Yang, Jianlong
AU - Liu, Gangjun
AU - Foster, Sarah
AU - Wang, Ruikang
AU - Nuttall, Alfred
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Using optical coherence tomography angiography, we measured blood flow from the vessels in the lateral wall in the mouse cochlea directly through bone in mice with and without sympathetic neuronal function. We present in vivo imaging of blood flow and mechanical vibration in mice subjected to 30 min of loud sound. Loud sound caused blood flow reduction. In mice with superior cervical ganglion ablation, the loud sound-induced reduction in blood flow was partially ameliorated. These results demonstrate that sympathetic innervation likely plays a role in the pathological decrease in blood flow observed in the lateral wall vessels in response to loud sound.
AB - Using optical coherence tomography angiography, we measured blood flow from the vessels in the lateral wall in the mouse cochlea directly through bone in mice with and without sympathetic neuronal function. We present in vivo imaging of blood flow and mechanical vibration in mice subjected to 30 min of loud sound. Loud sound caused blood flow reduction. In mice with superior cervical ganglion ablation, the loud sound-induced reduction in blood flow was partially ameliorated. These results demonstrate that sympathetic innervation likely plays a role in the pathological decrease in blood flow observed in the lateral wall vessels in response to loud sound.
KW - Blood flow
KW - Cochlea
KW - Imaging systems
KW - Medical optics and biotechnology
KW - Noiseinduced hearing loss
KW - Optical coherence tomography
UR - http://www.scopus.com/inward/record.url?scp=85059454007&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85059454007&partnerID=8YFLogxK
U2 - 10.1117/12.2505434
DO - 10.1117/12.2505434
M3 - Conference contribution
AN - SCOPUS:85059454007
VL - 10964
BT - Tenth International Conference on Information Optics and Photonics
A2 - Huang, Yidong
PB - SPIE
ER -