Analysis of small vessel cochlear blood flow regulation during loud sound exposure in the mouse

George W.S. Burwood, Suzan Dziennis, Teresa Wilson, Jianlong Yang, Gangjun Liu, Sarah Foster, Ruikang Wang, Alfred Nuttall

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Using optical coherence tomography angiography, we measured blood flow from the vessels in the lateral wall in the mouse cochlea directly through bone in mice with and without sympathetic neuronal function. We present in vivo imaging of blood flow and mechanical vibration in mice subjected to 30 min of loud sound. Loud sound caused blood flow reduction. In mice with superior cervical ganglion ablation, the loud sound-induced reduction in blood flow was partially ameliorated. These results demonstrate that sympathetic innervation likely plays a role in the pathological decrease in blood flow observed in the lateral wall vessels in response to loud sound.

Original languageEnglish (US)
Title of host publicationTenth International Conference on Information Optics and Photonics
EditorsYidong Huang
PublisherSPIE
Volume10964
ISBN (Electronic)9781510625792
DOIs
StatePublished - Jan 1 2018
Event10th International Conference on Information Optics and Photonics - Beijing, China
Duration: Jul 8 2018Jul 11 2018

Other

Other10th International Conference on Information Optics and Photonics
CountryChina
CityBeijing
Period7/8/187/11/18

Fingerprint

blood flow
Blood Flow
Vessel
vessels
mice
Mouse
Blood
Acoustic waves
acoustics
Lateral
cochlea
Optical Coherence Tomography
Angiography
angiography
Ablation
Optical tomography
Bone
bones
ablation
Vibration

Keywords

  • Blood flow
  • Cochlea
  • Imaging systems
  • Medical optics and biotechnology
  • Noiseinduced hearing loss
  • Optical coherence tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Burwood, G. W. S., Dziennis, S., Wilson, T., Yang, J., Liu, G., Foster, S., ... Nuttall, A. (2018). Analysis of small vessel cochlear blood flow regulation during loud sound exposure in the mouse. In Y. Huang (Ed.), Tenth International Conference on Information Optics and Photonics (Vol. 10964). [109641R] SPIE. https://doi.org/10.1117/12.2505434

Analysis of small vessel cochlear blood flow regulation during loud sound exposure in the mouse. / Burwood, George W.S.; Dziennis, Suzan; Wilson, Teresa; Yang, Jianlong; Liu, Gangjun; Foster, Sarah; Wang, Ruikang; Nuttall, Alfred.

Tenth International Conference on Information Optics and Photonics. ed. / Yidong Huang. Vol. 10964 SPIE, 2018. 109641R.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Burwood, GWS, Dziennis, S, Wilson, T, Yang, J, Liu, G, Foster, S, Wang, R & Nuttall, A 2018, Analysis of small vessel cochlear blood flow regulation during loud sound exposure in the mouse. in Y Huang (ed.), Tenth International Conference on Information Optics and Photonics. vol. 10964, 109641R, SPIE, 10th International Conference on Information Optics and Photonics, Beijing, China, 7/8/18. https://doi.org/10.1117/12.2505434
Burwood GWS, Dziennis S, Wilson T, Yang J, Liu G, Foster S et al. Analysis of small vessel cochlear blood flow regulation during loud sound exposure in the mouse. In Huang Y, editor, Tenth International Conference on Information Optics and Photonics. Vol. 10964. SPIE. 2018. 109641R https://doi.org/10.1117/12.2505434
Burwood, George W.S. ; Dziennis, Suzan ; Wilson, Teresa ; Yang, Jianlong ; Liu, Gangjun ; Foster, Sarah ; Wang, Ruikang ; Nuttall, Alfred. / Analysis of small vessel cochlear blood flow regulation during loud sound exposure in the mouse. Tenth International Conference on Information Optics and Photonics. editor / Yidong Huang. Vol. 10964 SPIE, 2018.
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