Abstract
Using optical coherence tomography angiography, we measured blood flow from the vessels in the lateral wall in the mouse cochlea directly through bone in mice with and without sympathetic neuronal function. We present in vivo imaging of blood flow and mechanical vibration in mice subjected to 30 min of loud sound. Loud sound caused blood flow reduction. In mice with superior cervical ganglion ablation, the loud sound-induced reduction in blood flow was partially ameliorated. These results demonstrate that sympathetic innervation likely plays a role in the pathological decrease in blood flow observed in the lateral wall vessels in response to loud sound.
Original language | English (US) |
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Title of host publication | Tenth International Conference on Information Optics and Photonics |
Editors | Yidong Huang |
Publisher | SPIE |
Volume | 10964 |
ISBN (Electronic) | 9781510625792 |
DOIs | |
State | Published - Jan 1 2018 |
Event | 10th International Conference on Information Optics and Photonics - Beijing, China Duration: Jul 8 2018 → Jul 11 2018 |
Other
Other | 10th International Conference on Information Optics and Photonics |
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Country | China |
City | Beijing |
Period | 7/8/18 → 7/11/18 |
Keywords
- Blood flow
- Cochlea
- Imaging systems
- Medical optics and biotechnology
- Noiseinduced hearing loss
- Optical coherence tomography
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering