Analysis of free-living mobility in people with mild traumatic brain injury and healthy controls: Quality over quantity

Samuel Stuart, Lucy Parrington, Douglas N. Martini, Nicholas Kreter, James C. Chesnutt, Peter C. Fino, Laurie A. King

Research output: Contribution to journalArticle

Abstract

Balance and mobility issues are common non-resolving symptoms following mild traumatic brain injury (mTBI). Current approaches for evaluating balance and mobility following an mTBI can be subjective and suboptimal as they may not be sensitive to subtle deficits, particularly in those with chronic mTBI. Wearable inertial measurement units (IMU) allow objective quantification of continuous mobility outcomes in natural free-living environments. This study aimed to explore free-living mobility (physical activity and turning) of healthy and chronic mild traumatic brain injury (mTBI) participants using a single IMU. Free-living mobility was examined in 23 healthy control (48.56 ± 23.07 years) and 29 symptomatic mTBI (40.2 ± 12.1 years) participants (average 419 days post-injury, persistent balance complaints) over 1 week, using a single IMU placed at the waist. Free-living mobility was characterized in terms of macro (physical activity volume, pattern and variability) and micro-level (discrete measures of turning) features. Macro-level outcomes showed those with chronic mTBI had similar quantities of mobility compared with controls. Micro-level outcomes within walking bouts showed that chronic mTBI participants had impaired quality of mobility. Specifically, people with chronic mTBI made larger turns, had longer turning durations, slower average and peak velocities (all p < 0.001), and greater turn variability compared with controls. Results highlighted that the quality rather than quantity of mobility differentiated chronic mTBI from controls. Our findings support the use of free-living IMU continuous monitoring to enhance understanding of specific chronic mTBI-related mobility deficits. Future work is required to develop an optimal battery of free-living measures across the mTBI spectrum to aid application within clinical practice.

Original languageEnglish (US)
Pages (from-to)139-145
Number of pages7
JournalJournal of neurotrauma
Volume37
Issue number1
DOIs
StatePublished - Jan 1 2020

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Brain Concussion
Quality Control
Walking

Keywords

  • concussion
  • free-living
  • mTBI
  • physical activity
  • turning
  • wearable sensor

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Analysis of free-living mobility in people with mild traumatic brain injury and healthy controls : Quality over quantity. / Stuart, Samuel; Parrington, Lucy; Martini, Douglas N.; Kreter, Nicholas; Chesnutt, James C.; Fino, Peter C.; King, Laurie A.

In: Journal of neurotrauma, Vol. 37, No. 1, 01.01.2020, p. 139-145.

Research output: Contribution to journalArticle

Stuart, Samuel ; Parrington, Lucy ; Martini, Douglas N. ; Kreter, Nicholas ; Chesnutt, James C. ; Fino, Peter C. ; King, Laurie A. / Analysis of free-living mobility in people with mild traumatic brain injury and healthy controls : Quality over quantity. In: Journal of neurotrauma. 2020 ; Vol. 37, No. 1. pp. 139-145.
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