An outbreak of tularemia in a colony of outdoor-housed rhesus macaques (Macaca mulatta)

Christie E. Ferrecchia, Lois Colgin, Kirk Andrews, Anne Lewis

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Abstract

    Since an epizootic and detection of clinical cases of tularemia (Francisella tularensis) in 1996 at the Oregon National Primate Research Center, only 8 cases were identified in the succeeding 13 y. However, within a period of 7 mo, primarily during Winter 2010, 6 rhesus macaques were confirmed positive for Francisella tularensis type B by the Centers for Disease Control and Prevention by culture and fluorescent antibody testing. All cases had similar gross pathologic findings, which included necrotizing splenitis and lymphadenitis. Recent colony management efforts have focused on minimizing nonhuman primate exposure to commonly observed reservoir species and controlling rodent access to corral-style housing. Strategies continue to evolve with regard to managing a large breeding colony of nonhuman primates in the presence of this threat.

    Original languageEnglish (US)
    Pages (from-to)316-321
    Number of pages6
    JournalComparative Medicine
    Volume62
    Issue number4
    StatePublished - Aug 2012

    Fingerprint

    tularemia
    Tularemia
    Macaca mulatta
    Francisella tularensis
    Primates
    Disease Outbreaks
    Disease control
    lymphadenitis
    Centers for Disease Control and Prevention
    Lymphadenitis
    antibody detection
    Centers for Disease Control and Prevention (U.S.)
    Breeding
    Rodentia
    rodents
    winter
    Antibodies
    breeding
    Testing
    Research

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)
    • veterinary(all)

    Cite this

    An outbreak of tularemia in a colony of outdoor-housed rhesus macaques (Macaca mulatta). / Ferrecchia, Christie E.; Colgin, Lois; Andrews, Kirk; Lewis, Anne.

    In: Comparative Medicine, Vol. 62, No. 4, 08.2012, p. 316-321.

    Research output: Contribution to journalArticle

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