TY - JOUR
T1 - An official ATS/IDSA statement
T2 - Diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases
AU - Griffith, David E.
AU - Aksamit, Timothy
AU - Brown-Elliott, Barbara A.
AU - Catanzaro, Antonino
AU - Daley, Charles
AU - Gordin, Fred
AU - Holland, Steven M.
AU - Horsburgh, Robert
AU - Huitt, Gwen
AU - Iademarco, Michael F.
AU - Iseman, Michael
AU - Olivier, Kenneth
AU - Ruoss, Stephen
AU - Von Reyn, C. Fordham
AU - Wallace, Richard J.
AU - Winthrop, Kevin
PY - 2007/2/15
Y1 - 2007/2/15
N2 - The minimum evaluation of a patient suspected of nontuberculous mycobacterial (NTM) lung disease should include the following: (1) chest radiograph or, in the absence of cavitation, chest high-resolution computed tomography (HRCT) scan; (2) three ormore sputumspecimens for acid-fast bacilli (AFB) analysis; and (3) exclusion of other disorders, such as tuberculosis (TB). Clinical, radiographic, and microbiologic criteria are equally important and all must be met to make a diagnosis of NTM lung disease. The following criteria apply to symptomatic patients with radiographic opacities, nodular or cavitary, or an HRCT scan that shows multifocal bronchiectasis with multiple small nodules. These criteria fit best with Mycobacterium avium complex (MAC), M. kansasii, and M. abscessus. There is not enough known about most other NTM to be certain that these diagnostic criteria are universally applicable for all NTM respiratory pathogens.
AB - The minimum evaluation of a patient suspected of nontuberculous mycobacterial (NTM) lung disease should include the following: (1) chest radiograph or, in the absence of cavitation, chest high-resolution computed tomography (HRCT) scan; (2) three ormore sputumspecimens for acid-fast bacilli (AFB) analysis; and (3) exclusion of other disorders, such as tuberculosis (TB). Clinical, radiographic, and microbiologic criteria are equally important and all must be met to make a diagnosis of NTM lung disease. The following criteria apply to symptomatic patients with radiographic opacities, nodular or cavitary, or an HRCT scan that shows multifocal bronchiectasis with multiple small nodules. These criteria fit best with Mycobacterium avium complex (MAC), M. kansasii, and M. abscessus. There is not enough known about most other NTM to be certain that these diagnostic criteria are universally applicable for all NTM respiratory pathogens.
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U2 - 10.1164/rccm.200604-571ST
DO - 10.1164/rccm.200604-571ST
M3 - Review article
C2 - 17277290
AN - SCOPUS:33847050904
SN - 1073-449X
VL - 175
SP - 367
EP - 416
JO - American journal of respiratory and critical care medicine
JF - American journal of respiratory and critical care medicine
IS - 4
ER -