An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance

Jacob J. Junco; Taylor Chen; Raushan Rashid; Maci Terrell; Vincent U. Gant; Matthew Miller; Rachel Rau; H. Daniel Lacorazza; Karen R. Rabin

doi:10.1038/s41375-020-01036-w

An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance

Jacob J. Junco, Taylor Chen, Raushan Rashid, Maci Terrell, Vincent U. Gant, Matthew Miller, Rachel Rau, H. Daniel Lacorazza, Karen R. Rabin

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Original language	English (US)
Pages (from-to)	1777-1781
Number of pages	5
Journal	Leukemia
Volume	35
Issue number	6
DOIs	https://doi.org/10.1038/s41375-020-01036-w
State	Published - Jun 2021
Externally published	Yes

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

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10.1038/s41375-020-01036-w

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title = "An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance",

author = "Junco, {Jacob J.} and Taylor Chen and Raushan Rashid and Maci Terrell and Gant, {Vincent U.} and Matthew Miller and Rachel Rau and Lacorazza, {H. Daniel} and Rabin, {Karen R.}",

note = "Funding Information: Acknowledgements This work was supported by an American Society of Hematology Scholar Award (JJJ); grant RP170074 from the Cancer Prevention and Research Institute of Texas (KRR); funding from the Lynch family (KRR); and by the National Cancer Institute, National Institutes of Health (R01 CA207086 to HDL). Flow cytometry assays were performed at the Research Flow Cytometry Core Facility of Texas Children{\textquoteright}s Cancer and Hematology Centers with the support from the Cytometry and Cell Sorting Core at Baylor College of Medicine with funding from the CPRIT Core Facility Support Award (CPRIT-RP180672), the NIH (CA125123 and RR024574), and the assistance of Joel M. Sederstrom. Flow assistance was also generously provided by Amos Gaikwad and Tatiana Goltsova. Histology was performed by the BCM Center for Comparative Medicine Comparative Pathology Laboratory with the assistance of Brian Simons. Microscope assistance was generously provided by Debananda Pati and Nenggang Zhang.",

year = "2021",

month = jun,

doi = "10.1038/s41375-020-01036-w",

language = "English (US)",

volume = "35",

pages = "1777--1781",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Nature Publishing Group",

number = "6",

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T1 - An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance

AU - Junco, Jacob J.

AU - Chen, Taylor

AU - Rashid, Raushan

AU - Terrell, Maci

AU - Gant, Vincent U.

AU - Miller, Matthew

AU - Rau, Rachel

AU - Lacorazza, H. Daniel

AU - Rabin, Karen R.

N1 - Funding Information: Acknowledgements This work was supported by an American Society of Hematology Scholar Award (JJJ); grant RP170074 from the Cancer Prevention and Research Institute of Texas (KRR); funding from the Lynch family (KRR); and by the National Cancer Institute, National Institutes of Health (R01 CA207086 to HDL). Flow cytometry assays were performed at the Research Flow Cytometry Core Facility of Texas Children’s Cancer and Hematology Centers with the support from the Cytometry and Cell Sorting Core at Baylor College of Medicine with funding from the CPRIT Core Facility Support Award (CPRIT-RP180672), the NIH (CA125123 and RR024574), and the assistance of Joel M. Sederstrom. Flow assistance was also generously provided by Amos Gaikwad and Tatiana Goltsova. Histology was performed by the BCM Center for Comparative Medicine Comparative Pathology Laboratory with the assistance of Brian Simons. Microscope assistance was generously provided by Debananda Pati and Nenggang Zhang.

PY - 2021/6

Y1 - 2021/6

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DO - 10.1038/s41375-020-01036-w

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AN - SCOPUS:85090782694

SN - 0887-6924

VL - 35

SP - 1777

EP - 1781

JO - Leukemia

JF - Leukemia

IS - 6

ER -

An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance

ASJC Scopus subject areas

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