An innovative system for 3D clinical photography in the resource-limited settings

Saharnaz Baghdadchi, Kimberly Liu, Jacquelyn Knapp, Gabriel Prager, Susannah Graves, Kevan Akrami, Rolanda Manuel, Rui Bastos, Erin Reid, Dennis Carson, Sadik Esener, Joseph Carson, Yu Tsueng Liu

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Background: Kaposi's sarcoma (KS) is the most frequently occurring cancer in Mozambique among men and the second most frequently occurring cancer among women. Effective therapeutic treatments for KS are poorly understood in this area. There is an unmet need to develop a simple but accurate tool for improved monitoring and diagnosis in a resource-limited setting. Standardized clinical photographs have been considered to be an essential part of the evaluation.Methods: When a therapeutic response is achieved, nodular KS often exhibits a reduction of the thickness without a change in the base area of the lesion. To evaluate the vertical space along with other characters of a KS lesion, we have created an innovative imaging system with a consumer light-field camera attached to a miniature " photography studio" adaptor. The image file can be further processed by computational methods for quantification.Results: With this novel imaging system, each high-quality 3D image was consistently obtained with a single camera shot at bedside by minimally trained personnel. After computational processing, all-focused photos and measurable 3D parameters were obtained. More than 80 KS image sets were processed in a semi-automated fashion.Conclusions: In this proof-of-concept study, the feasibility to use a simple, low-cost and user-friendly system has been established for future clinical study to monitor KS therapeutic response. This 3D imaging system can be also applied to obtain standardized clinical photographs for other diseases.

Original languageEnglish (US)
Article number169
JournalJournal of translational medicine
Volume12
Issue number1
DOIs
StatePublished - Jun 15 2014
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Baghdadchi, S., Liu, K., Knapp, J., Prager, G., Graves, S., Akrami, K., Manuel, R., Bastos, R., Reid, E., Carson, D., Esener, S., Carson, J., & Liu, Y. T. (2014). An innovative system for 3D clinical photography in the resource-limited settings. Journal of translational medicine, 12(1), [169]. https://doi.org/10.1186/1479-5876-12-169