An ancient developmental induction: Heat-shock proteins induced in sporulation and oogenesis

S. Kurtz, J. Rossi, L. Petko, S. Lindquist

Research output: Contribution to journalArticle

169 Citations (Scopus)

Abstract

Every eukaryotic and prokaryotic organism tested to date synthesizes a small number of heat-shock proteins in response to heat and other forms of stress. A particular pattern of heat-shock gene expression was observed during ascospore development in Saccharomyces: heat-shock proteins hsp26 and hsp84 were strongly induced, whereas hsp70, the most highly conserved of these proteins, was neither induced nor inducible by heat shock. Instead, two proteins related to hsp70 were induced. A strikingly similar pattern of expression occurs during oogenesis in Drosophila, suggesting that it may be one of the earliest developmental pathways to evolve in eukaryotic cells.

Original languageEnglish (US)
Pages (from-to)1154-1157
Number of pages4
JournalScience
Volume231
Issue number4742
StatePublished - 1986
Externally publishedYes

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Oogenesis
Heat-Shock Proteins
Hot Temperature
Shock
Small Heat-Shock Proteins
Saccharomyces
Eukaryotic Cells
Drosophila
Proteins
Gene Expression

ASJC Scopus subject areas

  • General

Cite this

Kurtz, S., Rossi, J., Petko, L., & Lindquist, S. (1986). An ancient developmental induction: Heat-shock proteins induced in sporulation and oogenesis. Science, 231(4742), 1154-1157.

An ancient developmental induction : Heat-shock proteins induced in sporulation and oogenesis. / Kurtz, S.; Rossi, J.; Petko, L.; Lindquist, S.

In: Science, Vol. 231, No. 4742, 1986, p. 1154-1157.

Research output: Contribution to journalArticle

Kurtz, S, Rossi, J, Petko, L & Lindquist, S 1986, 'An ancient developmental induction: Heat-shock proteins induced in sporulation and oogenesis', Science, vol. 231, no. 4742, pp. 1154-1157.
Kurtz, S. ; Rossi, J. ; Petko, L. ; Lindquist, S. / An ancient developmental induction : Heat-shock proteins induced in sporulation and oogenesis. In: Science. 1986 ; Vol. 231, No. 4742. pp. 1154-1157.
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