Abstract
The oxygen tension (pO2) of endolymph of the guinea pig cochlea was measured during exposure to loud sound (12 kHz or high-pass noise; 110 dB SPL up to 1h duration). A small, but significant, steady decline in mean pO2 was observed after both pure tone and high-pass noise exposure. The extent of the change in pO2 varied from 0-50% in individual animals. compared with unexposed control animals. All exposed animals had an extensive loss of compound action potential (CAP) thresholds at frequencies of 8-30 kHz. However, there was no relationship between the extent of the change in pO2 of endolymph and CAP threshold loss.
Original language | English (US) |
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Pages (from-to) | 71-79 |
Number of pages | 9 |
Journal | Acta Oto-Laryngologica |
Volume | 107 |
Issue number | 1-2 |
DOIs | |
State | Published - 1989 |
Externally published | Yes |
Keywords
- Acoustic trauma
- Endolymph
- Oxygen microelectrode
ASJC Scopus subject areas
- Otorhinolaryngology