Abstract
The oxygen tension (pO2) of endolymph of the guinea pig cochlea was measured during exposure to loud sound (12 kHz or high-pass noise; 110 dB SPL up to 1h duration). A small, but significant, steady decline in mean pO2 was observed after both pure tone and high-pass noise exposure. The extent of the change in pO2 varied from 0-50% in individual animals. compared with unexposed control animals. All exposed animals had an extensive loss of compound action potential (CAP) thresholds at frequencies of 8-30 kHz. However, there was no relationship between the extent of the change in pO2 of endolymph and CAP threshold loss.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 71-79 |
| Number of pages | 9 |
| Journal | Acta Oto-Laryngologica |
| Volume | 107 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Jan 1 1989 |
Keywords
- Acoustic trauma
- Endolymph
- Oxygen microelectrode
ASJC Scopus subject areas
- Otorhinolaryngology
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Thorne, P. R., & Nuttall, A. L. (1989). Alterations in oxygenation of cochlear endolymph during loud sound exposure. Acta Oto-Laryngologica, 107(1-2), 71-79. https://doi.org/10.3109/00016488909127481