Alopecia: Histologic diagnosis by transverse sections

S. F. Templeton, D. J. Santa Cruz, Alvin Jr Solomon

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Histologic evaluation for alopecia can be difficult and in part can be attributed to confusing categorization and limited information derived from examination of traditionally prepared biopsy specimens. The transverse section technique has many advantages, and with experience is the preferable method for evaluating specimens for alopecia. Using this technique, numerous follicles can easily be seen in one tissue profile allowing evaluation of follicular density, follicular unit morphology, and follicular growth dynamics, ie, anagen-telogen ratio. Specimens are categorized as scarring or nonscarring alopecia, and further diagnostic criteria discussed herein assist the pathologist in making specific diagnoses of nonscarring and scarring alopecias. Scarring alopecia may be primary or secondary, and primary scarring alopecias are further classified as lymphocyte-associated and neutrophil-associated. Although the clinical impression is very important in diagnosing alopecia, transversely sectioned biopsy specimens can greatly aid the diagnosis and management of patients with alopecia.

Original languageEnglish (US)
Pages (from-to)2-18
Number of pages17
JournalSeminars in Diagnostic Pathology
Volume13
Issue number1
StatePublished - 1996
Externally publishedYes

Fingerprint

Alopecia
Cicatrix
Biopsy
Neutrophils
Lymphocytes
Growth

Keywords

  • Alopecia
  • hair follicle
  • nonscarring alopecia
  • scarring alopecia
  • transverse sections

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Templeton, S. F., Santa Cruz, D. J., & Solomon, A. J. (1996). Alopecia: Histologic diagnosis by transverse sections. Seminars in Diagnostic Pathology, 13(1), 2-18.

Alopecia : Histologic diagnosis by transverse sections. / Templeton, S. F.; Santa Cruz, D. J.; Solomon, Alvin Jr.

In: Seminars in Diagnostic Pathology, Vol. 13, No. 1, 1996, p. 2-18.

Research output: Contribution to journalArticle

Templeton, SF, Santa Cruz, DJ & Solomon, AJ 1996, 'Alopecia: Histologic diagnosis by transverse sections', Seminars in Diagnostic Pathology, vol. 13, no. 1, pp. 2-18.
Templeton SF, Santa Cruz DJ, Solomon AJ. Alopecia: Histologic diagnosis by transverse sections. Seminars in Diagnostic Pathology. 1996;13(1):2-18.
Templeton, S. F. ; Santa Cruz, D. J. ; Solomon, Alvin Jr. / Alopecia : Histologic diagnosis by transverse sections. In: Seminars in Diagnostic Pathology. 1996 ; Vol. 13, No. 1. pp. 2-18.
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