Allergic patch test reactions associated with cosmetics: Retrospective analysis of cross-sectional data from the North American Contact Dermatitis Group, 2001-2004

Erin M. Warshaw, Heather J. Buchholz, Donald V. Belsito, Howard I. Maibach, Joseph F. Fowler, Robert L. Rietschel, Kathryn A. Zug, C. G Toby Mathias, Melanie D. Pratt, Denis Sasseville, Frances Storrs, James S. Taylor, Vincent A. DeLeo, James G. Marks

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Background: Allergy to cosmetics is common. Objectives: We sought to characterize patients with positive patch test reactions associated with a cosmetic source, to identify common allergens; and to explore gender and occupational associations. Methods: We performed a retrospective, cross-sectional analysis. Results: Of 6621 female and 3440 male patients, 1582 female (23.8%) and 611 of male (17.8%) patients had at least one allergic patch test reaction associated with a cosmetic source. Of "allergic" patients (>1 allergic reaction, n = 6815), females were 1.21 times more likely to have an allergic reaction associated with a cosmetic source than were male patients (p <.0001, 95% confidence interval [CI] 1.12-1.31). Within the "cosmetic allergic" group (n = 2243), head and neck involvement was significantly higher in female than in male patients (49.3% vs 23.7%, p <.0001). One hundred twenty-five patients had occupationally related allergic reactions associated with a cosmetic. Limitations: This study is limited by its cross-sectional, retrospective design. Conclusion: Of all patients studied, 21.8% had an allergic reaction associated with a cosmetic. Site of dermatitis, cosmetic categories, and specific allergens differed somewhat by gender.

Original languageEnglish (US)
Pages (from-to)23-38
Number of pages16
JournalJournal of the American Academy of Dermatology
Volume60
Issue number1
DOIs
StatePublished - Jan 2009

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Patch Tests
Contact Dermatitis
Cosmetics
Cross-Sectional Studies
Hypersensitivity
Allergens
Dermatitis
Neck
Head
Confidence Intervals

ASJC Scopus subject areas

  • Dermatology

Cite this

Allergic patch test reactions associated with cosmetics : Retrospective analysis of cross-sectional data from the North American Contact Dermatitis Group, 2001-2004. / Warshaw, Erin M.; Buchholz, Heather J.; Belsito, Donald V.; Maibach, Howard I.; Fowler, Joseph F.; Rietschel, Robert L.; Zug, Kathryn A.; Mathias, C. G Toby; Pratt, Melanie D.; Sasseville, Denis; Storrs, Frances; Taylor, James S.; DeLeo, Vincent A.; Marks, James G.

In: Journal of the American Academy of Dermatology, Vol. 60, No. 1, 01.2009, p. 23-38.

Research output: Contribution to journalArticle

Warshaw, EM, Buchholz, HJ, Belsito, DV, Maibach, HI, Fowler, JF, Rietschel, RL, Zug, KA, Mathias, CGT, Pratt, MD, Sasseville, D, Storrs, F, Taylor, JS, DeLeo, VA & Marks, JG 2009, 'Allergic patch test reactions associated with cosmetics: Retrospective analysis of cross-sectional data from the North American Contact Dermatitis Group, 2001-2004', Journal of the American Academy of Dermatology, vol. 60, no. 1, pp. 23-38. https://doi.org/10.1016/j.jaad.2008.07.056
Warshaw, Erin M. ; Buchholz, Heather J. ; Belsito, Donald V. ; Maibach, Howard I. ; Fowler, Joseph F. ; Rietschel, Robert L. ; Zug, Kathryn A. ; Mathias, C. G Toby ; Pratt, Melanie D. ; Sasseville, Denis ; Storrs, Frances ; Taylor, James S. ; DeLeo, Vincent A. ; Marks, James G. / Allergic patch test reactions associated with cosmetics : Retrospective analysis of cross-sectional data from the North American Contact Dermatitis Group, 2001-2004. In: Journal of the American Academy of Dermatology. 2009 ; Vol. 60, No. 1. pp. 23-38.
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AU - Maibach, Howard I.

AU - Fowler, Joseph F.

AU - Rietschel, Robert L.

AU - Zug, Kathryn A.

AU - Mathias, C. G Toby

AU - Pratt, Melanie D.

AU - Sasseville, Denis

AU - Storrs, Frances

AU - Taylor, James S.

AU - DeLeo, Vincent A.

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