All KLH preparations are not created equal

Arthur A. Vandenbark; Paul Yoshihara; Leslie Carveth; Denis R. Burger

doi:10.1016/0008-8749(81)90265-3

All KLH preparations are not created equal

Arthur A. Vandenbark, Paul Yoshihara, Leslie Carveth, Denis R. Burger

Neurology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Keyhole limpet hemocyanin (KLH) preparations used for dermal testing in human volunteers may contain factors which elicit false positive reactions. These factors can be associated with the hemolymph collection procedure and possibly to a change in collection beds by the limpet supplier. Rapid collection of hemolymph from animals obtained from specified limpet beds resulted in KLH which produced negligible dermal reactivity in normal individuals.

Original language	English (US)
Pages (from-to)	240-243
Number of pages	4
Journal	Cellular Immunology
Volume	60
Issue number	1
DOIs	https://doi.org/10.1016/0008-8749(81)90265-3
State	Published - May 1 1981

ASJC Scopus subject areas

Immunology

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@article{ea7e5dc96f764b7eb834403d9b4264fb,

title = "All KLH preparations are not created equal",

abstract = "Keyhole limpet hemocyanin (KLH) preparations used for dermal testing in human volunteers may contain factors which elicit false positive reactions. These factors can be associated with the hemolymph collection procedure and possibly to a change in collection beds by the limpet supplier. Rapid collection of hemolymph from animals obtained from specified limpet beds resulted in KLH which produced negligible dermal reactivity in normal individuals.",

author = "Vandenbark, {Arthur A.} and Paul Yoshihara and Leslie Carveth and Burger, {Denis R.}",

note = "Funding Information: {\textquoteright} Supported by V.A. Grant 648-l 164-03 from the Veterans Administration, and Grant AI-14699 from the National Institutes of Health. {\textquoteright} Abbreviations used: KLH, keyhole limpet hemocyanin; DLE, dialyzable leukocyte extract.",

year = "1981",

month = may,

day = "1",

doi = "10.1016/0008-8749(81)90265-3",

language = "English (US)",

volume = "60",

pages = "240--243",

journal = "Cellular Immunology",

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T1 - All KLH preparations are not created equal

AU - Vandenbark, Arthur A.

AU - Yoshihara, Paul

AU - Carveth, Leslie

AU - Burger, Denis R.

N1 - Funding Information: ’ Supported by V.A. Grant 648-l 164-03 from the Veterans Administration, and Grant AI-14699 from the National Institutes of Health. ’ Abbreviations used: KLH, keyhole limpet hemocyanin; DLE, dialyzable leukocyte extract.

PY - 1981/5/1

Y1 - 1981/5/1

N2 - Keyhole limpet hemocyanin (KLH) preparations used for dermal testing in human volunteers may contain factors which elicit false positive reactions. These factors can be associated with the hemolymph collection procedure and possibly to a change in collection beds by the limpet supplier. Rapid collection of hemolymph from animals obtained from specified limpet beds resulted in KLH which produced negligible dermal reactivity in normal individuals.

AB - Keyhole limpet hemocyanin (KLH) preparations used for dermal testing in human volunteers may contain factors which elicit false positive reactions. These factors can be associated with the hemolymph collection procedure and possibly to a change in collection beds by the limpet supplier. Rapid collection of hemolymph from animals obtained from specified limpet beds resulted in KLH which produced negligible dermal reactivity in normal individuals.

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U2 - 10.1016/0008-8749(81)90265-3

DO - 10.1016/0008-8749(81)90265-3

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AN - SCOPUS:0019497345

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VL - 60

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JO - Cellular Immunology

JF - Cellular Immunology

IS - 1

ER -

All KLH preparations are not created equal

Abstract

ASJC Scopus subject areas

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