Albumin is a better predictor of outcomes than body mass index following coronary artery bypass grafting

Castigliano Bhamidipati, Damien J. Lapar, Gaurav S. Mehta, John A. Kern, Gilbert R. Upchurch, Irving L. Kron, Gorav Ailawadi

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Objective: Body mass index (BMI) influences risk in coronary artery bypass grafting (CABG) patients, but albumin level is not collected by the Society of Thoracic Surgeons database. We postulate that preoperative albumin is a better predictor of mortality than BMI following CABG. Methods: BMI from patients with serum albumin level within 6 months of isolated CABG during 1995-2010 from our institutional databases were identified. Patients were stratified by National Heart, Lung, and Blood Institute (NHLBI) BMI class, and by preoperative albumin. Regression models were used to assess predictors of morbidity and mortality. Results: We analyzed 2,794 isolated CABG patients at our institution. Unadjusted mortality was highest with lowest BMI (P ≤.05), and in patients with 2-3 g/dL albumin (P =.02). Ejection fraction (EF) and intra-aortic balloon pump (IABP) use were similar despite BMI; however, EF was lowest and IABP use highest in the 2-3 g/dL albumin group (P <.001, respectively). Unlike BMI groups, increasing albumin was associated with lower major complication rates (P =.001). Similarly, adjusted mortality was not influenced by BMI (AOR 0.97, 95% CI 0.93-1.02), but increasing albumin levels reduced the adjusted odds of death (AOR 0.61, 95% CI 0.42-0.90). Conclusion: Albumin, more than body mass index, is associated with mortality and morbidity in isolated CABG recipients and may be a better indicator for outcomes.

Original languageEnglish (US)
Pages (from-to)626-634
Number of pages9
JournalSurgery
Volume150
Issue number4
DOIs
StatePublished - Oct 1 2011
Externally publishedYes

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Coronary Artery Bypass
Albumins
Body Mass Index
Mortality
Databases
National Heart, Lung, and Blood Institute (U.S.)
Morbidity
Serum Albumin

ASJC Scopus subject areas

  • Surgery

Cite this

Bhamidipati, C., Lapar, D. J., Mehta, G. S., Kern, J. A., Upchurch, G. R., Kron, I. L., & Ailawadi, G. (2011). Albumin is a better predictor of outcomes than body mass index following coronary artery bypass grafting. Surgery, 150(4), 626-634. https://doi.org/10.1016/j.surg.2011.07.056

Albumin is a better predictor of outcomes than body mass index following coronary artery bypass grafting. / Bhamidipati, Castigliano; Lapar, Damien J.; Mehta, Gaurav S.; Kern, John A.; Upchurch, Gilbert R.; Kron, Irving L.; Ailawadi, Gorav.

In: Surgery, Vol. 150, No. 4, 01.10.2011, p. 626-634.

Research output: Contribution to journalArticle

Bhamidipati, C, Lapar, DJ, Mehta, GS, Kern, JA, Upchurch, GR, Kron, IL & Ailawadi, G 2011, 'Albumin is a better predictor of outcomes than body mass index following coronary artery bypass grafting', Surgery, vol. 150, no. 4, pp. 626-634. https://doi.org/10.1016/j.surg.2011.07.056
Bhamidipati, Castigliano ; Lapar, Damien J. ; Mehta, Gaurav S. ; Kern, John A. ; Upchurch, Gilbert R. ; Kron, Irving L. ; Ailawadi, Gorav. / Albumin is a better predictor of outcomes than body mass index following coronary artery bypass grafting. In: Surgery. 2011 ; Vol. 150, No. 4. pp. 626-634.
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