Airway responsiveness in atopic dermatitis

Alan F. Barker, Carol A. Hirshman, Ray D'Silva, Jon Hanifin

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Twelve of 123 patients with atopic dermatitis (AD) were screened by questionnaire and spirometry for the absence of smoking, hay fever, and respiratory disorders. Seven of these 12 patients had a positive methacholine challenge test. None of eight patients with another skin disorder, psoriasis, screened in a similar fashion, had a positive methacholine challenge. We conclude that hyperresponsive airways are a frequent finding in patients with AD and that similar mechanisms may account for the cutaneous physiologic and pharmacologic abnormalities that have been observed in AD.

Original languageEnglish (US)
Pages (from-to)780-783
Number of pages4
JournalThe Journal of Allergy and Clinical Immunology
Issue number4
StatePublished - Apr 1991
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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