Aggressive sinonasal natural killer/T-cell lymphoma with hemophagocytic lymphohistiocytosis

Justin H. Turner; Myriam Loyo; Sandra Y. Lin

doi:10.1016/j.amjoto.2011.05.003

Aggressive sinonasal natural killer/T-cell lymphoma with hemophagocytic lymphohistiocytosis

Justin H. Turner, Myriam Loyo, Sandra Y. Lin

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Extranodal natural killer/T-cell lymphoma of the nasal cavity is a rare malignancy with poor overall prognosis. We report the case of a rapidly fatal natural killer/T-cell lymphoma of the nasal cavity complicated by the concominant development of hemophagocytic lymphohistiocytosis. This disorder is marked by clinical findings such as fever and splenomegaly, a multitude of abnormal laboratory findings, and a profound proliferation of circulating macrophages. Left untreated, multi-organ failure and death are common. Prompt diagnosis is essential to the successful management of this disorder and for subsequent recovery.

Original language	English (US)
Pages (from-to)	188-191
Number of pages	4
Journal	American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume	33
Issue number	1
DOIs	https://doi.org/10.1016/j.amjoto.2011.05.003
State	Published - Jan 2012
Externally published	Yes

ASJC Scopus subject areas

Otorhinolaryngology

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10.1016/j.amjoto.2011.05.003

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abstract = "Extranodal natural killer/T-cell lymphoma of the nasal cavity is a rare malignancy with poor overall prognosis. We report the case of a rapidly fatal natural killer/T-cell lymphoma of the nasal cavity complicated by the concominant development of hemophagocytic lymphohistiocytosis. This disorder is marked by clinical findings such as fever and splenomegaly, a multitude of abnormal laboratory findings, and a profound proliferation of circulating macrophages. Left untreated, multi-organ failure and death are common. Prompt diagnosis is essential to the successful management of this disorder and for subsequent recovery.",

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AB - Extranodal natural killer/T-cell lymphoma of the nasal cavity is a rare malignancy with poor overall prognosis. We report the case of a rapidly fatal natural killer/T-cell lymphoma of the nasal cavity complicated by the concominant development of hemophagocytic lymphohistiocytosis. This disorder is marked by clinical findings such as fever and splenomegaly, a multitude of abnormal laboratory findings, and a profound proliferation of circulating macrophages. Left untreated, multi-organ failure and death are common. Prompt diagnosis is essential to the successful management of this disorder and for subsequent recovery.

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Aggressive sinonasal natural killer/T-cell lymphoma with hemophagocytic lymphohistiocytosis

Abstract

ASJC Scopus subject areas

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