Abstract
ADENOMATOUS TUMORS OF the middle ear are rare, with only approximately 100 cases reported. A distinct subclass of this tumor demonstrates microscopic papillary architecture and has a propensity to erode the petrous bone and extend intracranially. The term “aggressive papillary middle ear tumor” has recently been proposed to describe this more invasive type of middle ear tumor. Thirty-seven cases of aggressive papillary middle ear tumors have been reported. We present two additional cases and discuss the clinical, radiologic, histologic, and operative features of this locally aggressive neoplasm. The tumor affects adults of both sexes. The clinical prodrome is prolonged. Presenting signs and symptoms most often relate to the involvement of cranial nerves V-VIII. Imaging studies reveal large, enhancing, destructive tumors with a generous vascular supply. Intraoperatively, the tumors are bloody, fibrous, and adherent to surrounding structures. Various surgical approaches in combination or in series may be used. Preoperative embolization may be helpful. The role of adjunctive radiation is unclear. Aggressive papillary middle ear tumors are histologically benign tumors with clinically destructive behavior. However, it appears that aggressive surgical management affords prolonged survival with minimal worsening of cranial nerve deficits.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 493-497 |
| Number of pages | 5 |
| Journal | Neurosurgery |
| Volume | 35 |
| Issue number | 3 |
| State | Published - 1994 |
| Externally published | Yes |
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Keywords
- Aggressive papillary middle ear tumor
- Cranial base surgery
- Endolymphatic sac tumor
- Petrosectomy
- Temporal bone
ASJC Scopus subject areas
- Clinical Neurology
- Surgery
Cite this
Aggressive papillary middle ear tumors : A report of two cases with review of the literature. / Polinsky, Michael N.; Brunberg, James A.; Mckeever, Paul E.; Sandler, Howard M.; Telian, Steven; Ross, Donald (Don).
In: Neurosurgery, Vol. 35, No. 3, 1994, p. 493-497.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Aggressive papillary middle ear tumors
T2 - A report of two cases with review of the literature
AU - Polinsky, Michael N.
AU - Brunberg, James A.
AU - Mckeever, Paul E.
AU - Sandler, Howard M.
AU - Telian, Steven
AU - Ross, Donald (Don)
PY - 1994
Y1 - 1994
N2 - ADENOMATOUS TUMORS OF the middle ear are rare, with only approximately 100 cases reported. A distinct subclass of this tumor demonstrates microscopic papillary architecture and has a propensity to erode the petrous bone and extend intracranially. The term “aggressive papillary middle ear tumor” has recently been proposed to describe this more invasive type of middle ear tumor. Thirty-seven cases of aggressive papillary middle ear tumors have been reported. We present two additional cases and discuss the clinical, radiologic, histologic, and operative features of this locally aggressive neoplasm. The tumor affects adults of both sexes. The clinical prodrome is prolonged. Presenting signs and symptoms most often relate to the involvement of cranial nerves V-VIII. Imaging studies reveal large, enhancing, destructive tumors with a generous vascular supply. Intraoperatively, the tumors are bloody, fibrous, and adherent to surrounding structures. Various surgical approaches in combination or in series may be used. Preoperative embolization may be helpful. The role of adjunctive radiation is unclear. Aggressive papillary middle ear tumors are histologically benign tumors with clinically destructive behavior. However, it appears that aggressive surgical management affords prolonged survival with minimal worsening of cranial nerve deficits.
AB - ADENOMATOUS TUMORS OF the middle ear are rare, with only approximately 100 cases reported. A distinct subclass of this tumor demonstrates microscopic papillary architecture and has a propensity to erode the petrous bone and extend intracranially. The term “aggressive papillary middle ear tumor” has recently been proposed to describe this more invasive type of middle ear tumor. Thirty-seven cases of aggressive papillary middle ear tumors have been reported. We present two additional cases and discuss the clinical, radiologic, histologic, and operative features of this locally aggressive neoplasm. The tumor affects adults of both sexes. The clinical prodrome is prolonged. Presenting signs and symptoms most often relate to the involvement of cranial nerves V-VIII. Imaging studies reveal large, enhancing, destructive tumors with a generous vascular supply. Intraoperatively, the tumors are bloody, fibrous, and adherent to surrounding structures. Various surgical approaches in combination or in series may be used. Preoperative embolization may be helpful. The role of adjunctive radiation is unclear. Aggressive papillary middle ear tumors are histologically benign tumors with clinically destructive behavior. However, it appears that aggressive surgical management affords prolonged survival with minimal worsening of cranial nerve deficits.
KW - Aggressive papillary middle ear tumor
KW - Cranial base surgery
KW - Endolymphatic sac tumor
KW - Petrosectomy
KW - Temporal bone
UR - http://www.scopus.com/inward/record.url?scp=0028069195&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028069195&partnerID=8YFLogxK
M3 - Article
C2 - 7800140
AN - SCOPUS:0028069195
VL - 35
SP - 493
EP - 497
JO - Neurosurgery
JF - Neurosurgery
SN - 0148-396X
IS - 3
ER -