Aggregation in amphiphilic macrocycle-substituted Gd3+ DOTA-type chelates is affected by the regiochemistry of substitution

Benjamin C. Webber, Claudio Cassino, Mauro Botta, Mark Woods

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Gd3+ chelates of macrocyclic bifunctional chelators (BFCs) can differentiate into two regioisomers: corner and side. These isomers afford different orientations of chelate relative to conjugate. These differences alter the self-assembly, tumbling, and effectiveness as magnetic resonance imaging contrast agents of the two biphenyl conjugate isomers.

Original languageEnglish (US)
Pages (from-to)2085-2087
Number of pages3
JournalInorganic Chemistry
Volume54
Issue number5
DOIs
StatePublished - Mar 2 2015

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ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry

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