TY - JOUR
T1 - Age-related changes in prefrontal white matter volume across adolescence
AU - Nagel, Bonnie J.
AU - Medina, Krista Lisdahl
AU - Yoshii, June
AU - Schweinsburg, Alecia D.
AU - Moadab, Ida
AU - Tapert, Susan F.
PY - 2006/9
Y1 - 2006/9
N2 - Past research has suggested that white matter volume increases from childhood to adulthood; however, during adolescence, there is somewhat limited data to support this finding. In the present study, 65 typically developing adolescents underwent structural magnetic resonance imaging. Using magnetic resonance imaging, prefrontal white matter volumes were examined in relation to adolescent age and sex. Surprisingly, results suggested that prefrontal white matter volume decreased during late adolescence, particularly among the female sex. These findings are inconsistent with past research and suggest that perhaps some developmental processes in late adolescence are not yet fully explained. Possible methodological contributions and implications for the current findings are discussed.
AB - Past research has suggested that white matter volume increases from childhood to adulthood; however, during adolescence, there is somewhat limited data to support this finding. In the present study, 65 typically developing adolescents underwent structural magnetic resonance imaging. Using magnetic resonance imaging, prefrontal white matter volumes were examined in relation to adolescent age and sex. Surprisingly, results suggested that prefrontal white matter volume decreased during late adolescence, particularly among the female sex. These findings are inconsistent with past research and suggest that perhaps some developmental processes in late adolescence are not yet fully explained. Possible methodological contributions and implications for the current findings are discussed.
KW - Adolescent development
KW - Frontal lobes
KW - Magnetic resonance imaging
KW - Segmentation
KW - White matter
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U2 - 10.1097/01.wnr.0000233099.97784.45
DO - 10.1097/01.wnr.0000233099.97784.45
M3 - Article
C2 - 16932152
AN - SCOPUS:33748067285
SN - 0959-4965
VL - 17
SP - 1427
EP - 1431
JO - NeuroReport
JF - NeuroReport
IS - 13
ER -