Advances in biomedical imaging, bioengineering, and related technologies for the development of biomarkers of pancreatic disease summary of a national institute of diabetes and digestive and kidney diseases and national institute of biomedical imaging and bioengineering workshop

Kimberly A. Kelly, Michael A. Hollingsworth, Randall E. Brand, Christina H. Liu, Vikesh K. Singh, Sudhir Srivastava, Ajay D. Wasan, Dhiraj Yadav, Dana Andersen

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Biomedical Imaging and Bioengineering focused on research gaps and opportunities in the development of new biomarkers of pancreatic disease. The session was held on July 22, 2015, and structured into 6 sessions: 1) Introduction and Overview; 2) Keynote Address; 3) New Approaches to the Diagnosis of Chronic Pancreatitis; 4) Biomarkers of Pain and Inflammation; 5) New Approaches to the Detection of Pancreatic Cancer; and 6) Shed Exosomes, Shed Cells, and Shed Proteins. Recent advances in the fields of pancreatic imaging, functional markers of pancreatic disease, proteomics, molecular and cellular imaging, and detection of circulating cancer cells and exosomes were reviewed. Knowledge gaps and research needs were highlighted. The development of new methods for the noninvasive determination of pancreatic pathology; the use of cellular markers of pancreatic function, inflammation, pain, and malignancy; and the refinement of methods to identify cells and cellular constituents of pancreatic cancer were discussed. The further refinement of sophisticated technical methods and the need for clinical studies to validate these new approaches in largescale studies of patients at risk for the development of pancreatic disease were repeatedly emphasized.

Original languageEnglish (US)
Pages (from-to)1185-1194
Number of pages10
JournalPancreas
Volume44
Issue number8
StatePublished - 2015
Externally publishedYes

Fingerprint

National Institute of Biomedical Imaging and Bioengineering (U.S.)
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Bioengineering
Pancreatic Diseases
Exosomes
Biomarkers
Technology
Pancreatic Neoplasms
Education
Inflammation
Pain
Molecular Imaging
Chronic Pancreatitis
Research
Proteomics
Neoplasms
Pathology
Proteins

Keywords

  • Biomarkers
  • Chronic pancreatitis
  • Circulating tumor cells
  • Exosomes
  • Molecular imaging
  • Pancreatic cancer

ASJC Scopus subject areas

  • Hepatology
  • Internal Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Advances in biomedical imaging, bioengineering, and related technologies for the development of biomarkers of pancreatic disease summary of a national institute of diabetes and digestive and kidney diseases and national institute of biomedical imaging and bioengineering workshop. / Kelly, Kimberly A.; Hollingsworth, Michael A.; Brand, Randall E.; Liu, Christina H.; Singh, Vikesh K.; Srivastava, Sudhir; Wasan, Ajay D.; Yadav, Dhiraj; Andersen, Dana.

In: Pancreas, Vol. 44, No. 8, 2015, p. 1185-1194.

Research output: Contribution to journalArticle

Kelly, Kimberly A. ; Hollingsworth, Michael A. ; Brand, Randall E. ; Liu, Christina H. ; Singh, Vikesh K. ; Srivastava, Sudhir ; Wasan, Ajay D. ; Yadav, Dhiraj ; Andersen, Dana. / Advances in biomedical imaging, bioengineering, and related technologies for the development of biomarkers of pancreatic disease summary of a national institute of diabetes and digestive and kidney diseases and national institute of biomedical imaging and bioengineering workshop. In: Pancreas. 2015 ; Vol. 44, No. 8. pp. 1185-1194.
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