Adult stem cells in small animal wound healing models

Allison C. Nauta, Geoffrey C. Gurtner, Michael T. Longaker

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Abstract

This chapter broadly reviews the use of stem cells as a means to accelerate wound healing, focusing first on the properties of stem cells that make them attractive agents to influence repair, both alone and as vehicles for growth factor delivery. Major stem cell reservoirs are described, including adult, embryonic, and induced pluripotent cell sources, outlining the advantages and limitations of each source as wound healing agents, as well as the possible mechanisms responsible for wound healing acceleration. Finally, the chapter includes a materials and methods section that provides an in-depth description of adult tissue harvest techniques.

Original languageEnglish (US)
Title of host publicationWound Regeneration and Repair
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Pages81-98
Number of pages18
ISBN (Print)9781627035040
DOIs
StatePublished - 2013
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume1037
ISSN (Print)1064-3745

Keywords

  • Adipose derived stromal cells
  • Adult stem cells
  • Bone marrow derived mesenchymal cells

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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