TY - CHAP
T1 - Adult stem cells in small animal wound healing models
AU - Nauta, Allison C.
AU - Gurtner, Geoffrey C.
AU - Longaker, Michael T.
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - This chapter broadly reviews the use of stem cells as a means to accelerate wound healing, focusing first on the properties of stem cells that make them attractive agents to influence repair, both alone and as vehicles for growth factor delivery. Major stem cell reservoirs are described, including adult, embryonic, and induced pluripotent cell sources, outlining the advantages and limitations of each source as wound healing agents, as well as the possible mechanisms responsible for wound healing acceleration. Finally, the chapter includes a materials and methods section that provides an in-depth description of adult tissue harvest techniques.
AB - This chapter broadly reviews the use of stem cells as a means to accelerate wound healing, focusing first on the properties of stem cells that make them attractive agents to influence repair, both alone and as vehicles for growth factor delivery. Major stem cell reservoirs are described, including adult, embryonic, and induced pluripotent cell sources, outlining the advantages and limitations of each source as wound healing agents, as well as the possible mechanisms responsible for wound healing acceleration. Finally, the chapter includes a materials and methods section that provides an in-depth description of adult tissue harvest techniques.
KW - Adipose derived stromal cells
KW - Adult stem cells
KW - Bone marrow derived mesenchymal cells
UR - http://www.scopus.com/inward/record.url?scp=84934440618&partnerID=8YFLogxK
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U2 - 10.1007/978-1-62703-505-7_5
DO - 10.1007/978-1-62703-505-7_5
M3 - Chapter
C2 - 24029931
AN - SCOPUS:84934440618
SN - 9781627035040
T3 - Methods in Molecular Biology
SP - 81
EP - 98
BT - Wound Regeneration and Repair
PB - Humana Press Inc.
ER -