TY - JOUR
T1 - Adoption of an adult environmental neurobehavioral test battery
AU - Amler, Robert W.
AU - Lybarger, Jeffrey A.
AU - Anger, W. Kent
AU - Phifer, Betty L.
AU - Chappell, Willard
AU - Hutchinson, Leslie
N1 - Funding Information:
This pubfication was supported wholly by funds from the Comprehensive Environmental Response, Compensation, and Liability Act trust fund through the Agency for Toxic Substances and Disease Registry, Public Health Service, U.S. Department of Health and Human Services.
PY - 1994
Y1 - 1994
N2 - Nationally recognized experts participated in a 3-day workshop to discuss the complex issues associated with neurobehavioral testing in environmental health settings, and to propose basic and focused test batteries for use in evaluating populations living near hazardous chemical sites. The Adult Environmental Neurobehavioral Test Battery (AENTB), which evaluates major neurobehavioral domains and functions, was adopted by the Agency for Toxic Substances and Disease Registry (ATSDR) for use as a basic screening panel in field studies. Pilot testing of the AENTB demonstrated an examiner training requirement of 3-6 practice sessions, a mean total testing time of 58.0 min (SD = 9.6), and, for 9 of the component tests, a sample size requirement of fewer than 140 (α = 0.05,95% power) to detect a 20% difference between study groups. ATSDR administered the AENTB to 467 persons, selected randomly from 1,382 participants in field study sites in three states. Total testing time varied noticeably by participant age and study site, suggesting an ongoing need for site-specific controls in each field study using the AENTB. Also planned is adoption of a pediatric test battery to evaluate the domains and functions most relevant at major stages of child development.
AB - Nationally recognized experts participated in a 3-day workshop to discuss the complex issues associated with neurobehavioral testing in environmental health settings, and to propose basic and focused test batteries for use in evaluating populations living near hazardous chemical sites. The Adult Environmental Neurobehavioral Test Battery (AENTB), which evaluates major neurobehavioral domains and functions, was adopted by the Agency for Toxic Substances and Disease Registry (ATSDR) for use as a basic screening panel in field studies. Pilot testing of the AENTB demonstrated an examiner training requirement of 3-6 practice sessions, a mean total testing time of 58.0 min (SD = 9.6), and, for 9 of the component tests, a sample size requirement of fewer than 140 (α = 0.05,95% power) to detect a 20% difference between study groups. ATSDR administered the AENTB to 467 persons, selected randomly from 1,382 participants in field study sites in three states. Total testing time varied noticeably by participant age and study site, suggesting an ongoing need for site-specific controls in each field study using the AENTB. Also planned is adoption of a pediatric test battery to evaluate the domains and functions most relevant at major stages of child development.
KW - ATSDR
KW - Behavioral tests
KW - Environmental health study
KW - Environmental toxicology
KW - Hazardous substances
KW - Neurotoxic disorders
KW - Pollution
KW - Superfund
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U2 - 10.1016/0892-0362(94)90131-7
DO - 10.1016/0892-0362(94)90131-7
M3 - Article
C2 - 7845335
AN - SCOPUS:0028101126
SN - 0892-0362
VL - 16
SP - 525
EP - 530
JO - Neurotoxicology and Teratology
JF - Neurotoxicology and Teratology
IS - 5
ER -