Adjuncts to preparing wounds for closure Hyperbaric oxygen, growth factors, skin substitutes, negative pressure wound therapy (vacuum-assisted closure)

Harriet W. Hopf, Lisa M. Humphrey, Nancy Puzziferri, Judith M. West, Christopher E. Attinger, Thomas K. Hunt

Research output: Contribution to journalReview articlepeer-review

41 Scopus citations

Abstract

Achieving closure in a chronic wound requires provision of adequate oxygen delivery to the tissue, adequate protein and other nutritional factors, a moist environment, an appropriate inflammatory milieu, dèbridement, and correction of contributing medical diagnoses. In some patients, these conditions are achieved easily, whereas in others, greater effort is required. Adjunctive treatments, including HBO2, growth factors, skin substitutes, and negative-pressure wound therapy (eg, V.A.C.) can provide the proper conditions for healing in appropriately selected patients.

Original languageEnglish (US)
Pages (from-to)661-682
Number of pages22
JournalFoot and Ankle Clinics
Volume6
Issue number4
DOIs
StatePublished - Dec 2001
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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