Adenoma detection rate increases with each decade of life after 50 years of age

Sarah Diamond, Brintha Enestvedt, Zibing Jiang, Jennifer L. Holub, Maneesh Gupta, David Lieberman, Glenn M. Eisen

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Background: The adenoma detection rate (ADR) has recently been used as a quality measure for screening colonoscopy. We hypothesize that the ADR will increase with each decade of life after 50 years of age. Objective: The aim of this study was to define age-based goals for the ADR and advanced neoplasia to improve the quality of colonoscopy. Methods: Using the Clinical Outcomes Research Initiative database, we identified patients who underwent screening colonoscopy between 2005 and 2006. Pathology of polyp findings was reviewed, and the ADR and the prevalence of advanced neoplasia were calculated based on age and sex. Results: A total of 7756 polypectomies (44.9%) were performed on 17,275 patients between 2005 and 2006. Of these polyps, 56.3% (4363) were adenomas or more advanced lesions. The ADR was higher in men than women and increased with age. The ADR in men younger than age 50 was 24.7 (95% CI, 18.2-31.2); for those 50 to 59 years of age, it was 27.8 (95% CI, 26.5-29.1); for those 60 to 69 years of age, it was 33.6 (95% CI, 31.7-35.4); for those 70 to 79 years of age, it was 34.3 (95% CI, 31.5-37.1); and for those older than 80 years of age, it was 40.0 (95% CI, 32.9-47.1). The ADR in women younger than 50 years old was 12.6 (95% CI, 6.8-18.4); in those 50 to 59 years of age, it was 17.0 (85% CI, 15.9-18.1); for those 60 to 69 years of age, it was 22.4 (95% CI, 20.8-24.0); for those 70 to 79 years of age, it was 26.1 (95% CI, 23.7-28.5); and for those older than 80 years of age, it was 26.9 (95% CI, 21.4-32.5). Limitations: The Clinical Outcomes Research Initiative database offers access to demographic information as well as endoscopy and pathology data, but there is limited clinical information about patients in the database. Conclusion: The ADR, and, importantly, the rate of advanced neoplasia increased with each decade of life after the age of 50 and are higher in men than women in each decade of life.

Original languageEnglish (US)
Pages (from-to)135-140
Number of pages6
JournalGastrointestinal Endoscopy
Volume74
Issue number1
DOIs
StatePublished - Jul 2011

Fingerprint

Adenoma
Colonoscopy
Databases
Polyps
Outcome Assessment (Health Care)
Pathology
Neoplasms
Access to Information
Endoscopy
Demography

ASJC Scopus subject areas

  • Gastroenterology
  • Radiology Nuclear Medicine and imaging

Cite this

Adenoma detection rate increases with each decade of life after 50 years of age. / Diamond, Sarah; Enestvedt, Brintha; Jiang, Zibing; Holub, Jennifer L.; Gupta, Maneesh; Lieberman, David; Eisen, Glenn M.

In: Gastrointestinal Endoscopy, Vol. 74, No. 1, 07.2011, p. 135-140.

Research output: Contribution to journalArticle

Diamond, Sarah ; Enestvedt, Brintha ; Jiang, Zibing ; Holub, Jennifer L. ; Gupta, Maneesh ; Lieberman, David ; Eisen, Glenn M. / Adenoma detection rate increases with each decade of life after 50 years of age. In: Gastrointestinal Endoscopy. 2011 ; Vol. 74, No. 1. pp. 135-140.
@article{b323e08ac7a74f889503d3cbbb785fa0,
title = "Adenoma detection rate increases with each decade of life after 50 years of age",
abstract = "Background: The adenoma detection rate (ADR) has recently been used as a quality measure for screening colonoscopy. We hypothesize that the ADR will increase with each decade of life after 50 years of age. Objective: The aim of this study was to define age-based goals for the ADR and advanced neoplasia to improve the quality of colonoscopy. Methods: Using the Clinical Outcomes Research Initiative database, we identified patients who underwent screening colonoscopy between 2005 and 2006. Pathology of polyp findings was reviewed, and the ADR and the prevalence of advanced neoplasia were calculated based on age and sex. Results: A total of 7756 polypectomies (44.9{\%}) were performed on 17,275 patients between 2005 and 2006. Of these polyps, 56.3{\%} (4363) were adenomas or more advanced lesions. The ADR was higher in men than women and increased with age. The ADR in men younger than age 50 was 24.7 (95{\%} CI, 18.2-31.2); for those 50 to 59 years of age, it was 27.8 (95{\%} CI, 26.5-29.1); for those 60 to 69 years of age, it was 33.6 (95{\%} CI, 31.7-35.4); for those 70 to 79 years of age, it was 34.3 (95{\%} CI, 31.5-37.1); and for those older than 80 years of age, it was 40.0 (95{\%} CI, 32.9-47.1). The ADR in women younger than 50 years old was 12.6 (95{\%} CI, 6.8-18.4); in those 50 to 59 years of age, it was 17.0 (85{\%} CI, 15.9-18.1); for those 60 to 69 years of age, it was 22.4 (95{\%} CI, 20.8-24.0); for those 70 to 79 years of age, it was 26.1 (95{\%} CI, 23.7-28.5); and for those older than 80 years of age, it was 26.9 (95{\%} CI, 21.4-32.5). Limitations: The Clinical Outcomes Research Initiative database offers access to demographic information as well as endoscopy and pathology data, but there is limited clinical information about patients in the database. Conclusion: The ADR, and, importantly, the rate of advanced neoplasia increased with each decade of life after the age of 50 and are higher in men than women in each decade of life.",
author = "Sarah Diamond and Brintha Enestvedt and Zibing Jiang and Holub, {Jennifer L.} and Maneesh Gupta and David Lieberman and Eisen, {Glenn M.}",
year = "2011",
month = "7",
doi = "10.1016/j.gie.2011.03.1178",
language = "English (US)",
volume = "74",
pages = "135--140",
journal = "Gastrointestinal Endoscopy",
issn = "0016-5107",
publisher = "Mosby Inc.",
number = "1",

}

TY - JOUR

T1 - Adenoma detection rate increases with each decade of life after 50 years of age

AU - Diamond, Sarah

AU - Enestvedt, Brintha

AU - Jiang, Zibing

AU - Holub, Jennifer L.

AU - Gupta, Maneesh

AU - Lieberman, David

AU - Eisen, Glenn M.

PY - 2011/7

Y1 - 2011/7

N2 - Background: The adenoma detection rate (ADR) has recently been used as a quality measure for screening colonoscopy. We hypothesize that the ADR will increase with each decade of life after 50 years of age. Objective: The aim of this study was to define age-based goals for the ADR and advanced neoplasia to improve the quality of colonoscopy. Methods: Using the Clinical Outcomes Research Initiative database, we identified patients who underwent screening colonoscopy between 2005 and 2006. Pathology of polyp findings was reviewed, and the ADR and the prevalence of advanced neoplasia were calculated based on age and sex. Results: A total of 7756 polypectomies (44.9%) were performed on 17,275 patients between 2005 and 2006. Of these polyps, 56.3% (4363) were adenomas or more advanced lesions. The ADR was higher in men than women and increased with age. The ADR in men younger than age 50 was 24.7 (95% CI, 18.2-31.2); for those 50 to 59 years of age, it was 27.8 (95% CI, 26.5-29.1); for those 60 to 69 years of age, it was 33.6 (95% CI, 31.7-35.4); for those 70 to 79 years of age, it was 34.3 (95% CI, 31.5-37.1); and for those older than 80 years of age, it was 40.0 (95% CI, 32.9-47.1). The ADR in women younger than 50 years old was 12.6 (95% CI, 6.8-18.4); in those 50 to 59 years of age, it was 17.0 (85% CI, 15.9-18.1); for those 60 to 69 years of age, it was 22.4 (95% CI, 20.8-24.0); for those 70 to 79 years of age, it was 26.1 (95% CI, 23.7-28.5); and for those older than 80 years of age, it was 26.9 (95% CI, 21.4-32.5). Limitations: The Clinical Outcomes Research Initiative database offers access to demographic information as well as endoscopy and pathology data, but there is limited clinical information about patients in the database. Conclusion: The ADR, and, importantly, the rate of advanced neoplasia increased with each decade of life after the age of 50 and are higher in men than women in each decade of life.

AB - Background: The adenoma detection rate (ADR) has recently been used as a quality measure for screening colonoscopy. We hypothesize that the ADR will increase with each decade of life after 50 years of age. Objective: The aim of this study was to define age-based goals for the ADR and advanced neoplasia to improve the quality of colonoscopy. Methods: Using the Clinical Outcomes Research Initiative database, we identified patients who underwent screening colonoscopy between 2005 and 2006. Pathology of polyp findings was reviewed, and the ADR and the prevalence of advanced neoplasia were calculated based on age and sex. Results: A total of 7756 polypectomies (44.9%) were performed on 17,275 patients between 2005 and 2006. Of these polyps, 56.3% (4363) were adenomas or more advanced lesions. The ADR was higher in men than women and increased with age. The ADR in men younger than age 50 was 24.7 (95% CI, 18.2-31.2); for those 50 to 59 years of age, it was 27.8 (95% CI, 26.5-29.1); for those 60 to 69 years of age, it was 33.6 (95% CI, 31.7-35.4); for those 70 to 79 years of age, it was 34.3 (95% CI, 31.5-37.1); and for those older than 80 years of age, it was 40.0 (95% CI, 32.9-47.1). The ADR in women younger than 50 years old was 12.6 (95% CI, 6.8-18.4); in those 50 to 59 years of age, it was 17.0 (85% CI, 15.9-18.1); for those 60 to 69 years of age, it was 22.4 (95% CI, 20.8-24.0); for those 70 to 79 years of age, it was 26.1 (95% CI, 23.7-28.5); and for those older than 80 years of age, it was 26.9 (95% CI, 21.4-32.5). Limitations: The Clinical Outcomes Research Initiative database offers access to demographic information as well as endoscopy and pathology data, but there is limited clinical information about patients in the database. Conclusion: The ADR, and, importantly, the rate of advanced neoplasia increased with each decade of life after the age of 50 and are higher in men than women in each decade of life.

UR - http://www.scopus.com/inward/record.url?scp=79959715791&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79959715791&partnerID=8YFLogxK

U2 - 10.1016/j.gie.2011.03.1178

DO - 10.1016/j.gie.2011.03.1178

M3 - Article

C2 - 21612774

AN - SCOPUS:79959715791

VL - 74

SP - 135

EP - 140

JO - Gastrointestinal Endoscopy

JF - Gastrointestinal Endoscopy

SN - 0016-5107

IS - 1

ER -