Adenine aminohydrolase from Leishmania donovani. Unique enzyme in parasite purine metabolism

Medicine & Life Sciences

• adenine deaminase 100%
• Leishmania donovani 71%
• purine 60%
• Parasites 43%
• Enzymes 28%
• Pentostatin 16%
• human ADA protein 9%
• Purine Nucleosides 7%
• Parasite Load 7%
• Deamination 6%
• Hypoxanthine 6%
• Adenine 6%
• Leishmania 6%
• Essential Genes 5%
• Life Cycle Stages 5%
• Adenosine 5%
• Cytosol 5%
• Infections 5%
• Saccharomyces cerevisiae 4%
• Fluorescent Antibody Technique 4%
• Macrophages 3%
• Western Blotting 3%
• Growth 2%
• In Vitro Techniques 2%

Chemical Compounds

• Purine 52%
• Adenine 48%
• Pharmacological Metabolism 40%
• Adenosine 9%
• 6-Aminopurines 8%
• Purine Nucleobase 7%
• Purine Nucleoside 6%
• Km 5%
• Hypoxanthine 5%
• Lethal 5%
• Deamination 5%
• Ablation 5%
• Mammalian Cell 4%
• Fractionation 4%