Acute reversible lens opacity: Caused by drugs, cold, anoxia, asphyxia, stress, death and dehydration

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Acute experimental lens opacities reported to be caused by narcotics, phenothiazines, epinephrine, anoxia, and certain types of lens opacities induced by death, asphyxia, cold or stress are prevented by closure of the animal's eyelids. An unawareness of the importance of eyelid position has led to confusion concerning the pathogenesis of many of these lens changes. Most of these experimental cataracts can be classified into a single group with common characteristics, for which we propose the term "acute reversible lens opacity". The opacity is a reversible loss of transparency of the superficial anterior lens cortex which is prevented by closure of the eyelids. This type of cataract may be produced by mechanical methods or agents which interfere with lid closure or depress the blink reflex. The lens opacity may regress even though the initiating stimulus is maintained. Although dehydration of the aqueous humor and lens is the most important factor in development of the lens transparency change, there are other factors which also play a role.

Original languageEnglish (US)
Pages (from-to)19-30
Number of pages12
JournalExperimental Eye Research
Volume10
Issue number1
DOIs
StatePublished - 1970

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Asphyxia
Dehydration
Cataract
Lenses
Eyelids
Pharmaceutical Preparations
Phenothiazines
Blinking
Aqueous Humor
Narcotics
Epinephrine
Hypoxia

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Acute reversible lens opacity : Caused by drugs, cold, anoxia, asphyxia, stress, death and dehydration. / Fraunfelder, Frederick (Fritz); Burns, R. P.

In: Experimental Eye Research, Vol. 10, No. 1, 1970, p. 19-30.

Research output: Contribution to journalArticle

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