Acute renal failure following cocaine abuse

P. Singhal, B (Zane) Horowitz, M. C. Quinones, M. Sommer, M. Faulkner, M. Grosser

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Three healthy adult males developed acute renal failure following cocaine abuse. Muscle pain, tenderness, elevated levels of serum muscle enzymes, heme-positive urine and the presence of pigmented granular casts in urine all indicated occurrence of rhabdomyolysis. One of them developed acute compartmental syndrome of the left leg and required emergency fasciotomy. The course of renal failure and fast recovery were suggestive of acute tubular necrosis in all 3 patients. A possible role of cocaine in the aggravation of renal and/or muscle ischaemia has been speculated.

Original languageEnglish (US)
Pages (from-to)76-78
Number of pages3
JournalNephron
Volume52
Issue number1
StatePublished - 1989
Externally publishedYes

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Cocaine-Related Disorders
Acute Kidney Injury
Urine
Muscles
Rhabdomyolysis
Myalgia
Heme
Cocaine
Renal Insufficiency
Leg
Emergencies
Necrosis
Ischemia
Kidney
Enzymes
Serum
Fasciotomy

ASJC Scopus subject areas

  • Nephrology

Cite this

Singhal, P., Horowitz, B. Z., Quinones, M. C., Sommer, M., Faulkner, M., & Grosser, M. (1989). Acute renal failure following cocaine abuse. Nephron, 52(1), 76-78.

Acute renal failure following cocaine abuse. / Singhal, P.; Horowitz, B (Zane); Quinones, M. C.; Sommer, M.; Faulkner, M.; Grosser, M.

In: Nephron, Vol. 52, No. 1, 1989, p. 76-78.

Research output: Contribution to journalArticle

Singhal, P, Horowitz, BZ, Quinones, MC, Sommer, M, Faulkner, M & Grosser, M 1989, 'Acute renal failure following cocaine abuse', Nephron, vol. 52, no. 1, pp. 76-78.
Singhal P, Horowitz BZ, Quinones MC, Sommer M, Faulkner M, Grosser M. Acute renal failure following cocaine abuse. Nephron. 1989;52(1):76-78.
Singhal, P. ; Horowitz, B (Zane) ; Quinones, M. C. ; Sommer, M. ; Faulkner, M. ; Grosser, M. / Acute renal failure following cocaine abuse. In: Nephron. 1989 ; Vol. 52, No. 1. pp. 76-78.
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