Acute lung disease in the immunocompromised host: Diagnostic accuracy of the chest radiograph

P. M. Logan, Steven Primack, C. Staples, R. R. Miller, N. L. Muller

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Purpose: To assess the diagnostic accuracy of the chest radiograph in the evaluation of acute pulmonary complications in immunocompromised patients. Methods: The study included the chest radiographs in 149 consecutive acute pulmonary complications seen in immunocompromised patients in whom a definitive diagnosis was made. Twenty-four complications were in patients with AIDS and 125 were in non-AIDS patients. The radiographs were separately reviewed in random order by two independent observers. The observers assessed pattern and distribution of radiographic findings and recorded their first- choice diagnosis. Results: The most common complication in patients with AIDS was Pneumocystis carinii pneumonia (n=21). In the non-AIDS patients, the most common complications included invasive aspergillosis (n=25), drug reaction (n=21), and Pneumocystis pneumonia (n=20). A correct first-choice diagnosis was made in 90% of patients with AIDS and 34% of non-AIDS patients. In AIDS patients with Pneumocystis pneumonia, the correct first-choice diagnosis was made in 41 of 42 (98%) readings by the two observers. In non-AIDS patients with invasive pulmonary aspergillosis, drug reaction, and Pneumocystis pneumonia, the correct first-choice diagnosis was made in 38%, 26%, and 43% of readings, respectively. Conclusion: The chest radiograph is helpful in the differential diagnosis of acute lung disease in the immunocompromised host, particularly in patients with AIDS.

Original languageEnglish (US)
Pages (from-to)1283-1287
Number of pages5
JournalChest
Volume108
Issue number5
StatePublished - 1995
Externally publishedYes

Fingerprint

Immunocompromised Host
Acute Disease
Lung Diseases
Thorax
Pneumocystis Pneumonia
Acquired Immunodeficiency Syndrome
Reading
Invasive Pulmonary Aspergillosis
Lung
Aspergillosis
Pharmaceutical Preparations
Differential Diagnosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Logan, P. M., Primack, S., Staples, C., Miller, R. R., & Muller, N. L. (1995). Acute lung disease in the immunocompromised host: Diagnostic accuracy of the chest radiograph. Chest, 108(5), 1283-1287.

Acute lung disease in the immunocompromised host : Diagnostic accuracy of the chest radiograph. / Logan, P. M.; Primack, Steven; Staples, C.; Miller, R. R.; Muller, N. L.

In: Chest, Vol. 108, No. 5, 1995, p. 1283-1287.

Research output: Contribution to journalArticle

Logan, PM, Primack, S, Staples, C, Miller, RR & Muller, NL 1995, 'Acute lung disease in the immunocompromised host: Diagnostic accuracy of the chest radiograph', Chest, vol. 108, no. 5, pp. 1283-1287.
Logan, P. M. ; Primack, Steven ; Staples, C. ; Miller, R. R. ; Muller, N. L. / Acute lung disease in the immunocompromised host : Diagnostic accuracy of the chest radiograph. In: Chest. 1995 ; Vol. 108, No. 5. pp. 1283-1287.
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