Acute cholecystitis

Elizabeth Fialkowski, Valerie Halpin, Robb R. Whinney

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

INTRODUCTION: Of people admitted to hospital for biliary tract disease, 20% have acute cholecystitis. Up to the age of 50 years, acute calculous cholecystitis is three times more common in women than in men, and about 1.5 times more common in women than in men thereafter. About 95% of people with acute cholecystitis have gallstones. Optimal therapy for acute cholecystitis, based on timing and severity of presentation, remains controversial.

METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for acute cholecystitis? We searched: Medline, Embase, The Cochrane Library, and other important databases up to December 2006 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).

RESULTS: We found 12 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.

CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: early cholecystectomy, laparoscopic cholecystectomy, minilaparoscopic cholecystectomy, observation alone, and open cholecystectomy.

Original languageEnglish (US)
JournalBMJ clinical evidence
Volume2008
StatePublished - 2008
Externally publishedYes

Fingerprint

Acute Cholecystitis
Cholecystectomy
Biliary Tract Diseases
Laparoscopic Cholecystectomy
Gallstones
United States Food and Drug Administration
Libraries
Observational Studies
Observation
Organizations
Databases
Delivery of Health Care
Safety
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fialkowski, E., Halpin, V., & Whinney, R. R. (2008). Acute cholecystitis. BMJ clinical evidence, 2008.

Acute cholecystitis. / Fialkowski, Elizabeth; Halpin, Valerie; Whinney, Robb R.

In: BMJ clinical evidence, Vol. 2008, 2008.

Research output: Contribution to journalReview article

Fialkowski, E, Halpin, V & Whinney, RR 2008, 'Acute cholecystitis', BMJ clinical evidence, vol. 2008.
Fialkowski E, Halpin V, Whinney RR. Acute cholecystitis. BMJ clinical evidence. 2008;2008.
Fialkowski, Elizabeth ; Halpin, Valerie ; Whinney, Robb R. / Acute cholecystitis. In: BMJ clinical evidence. 2008 ; Vol. 2008.
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