Activation and repression in the nervous system

Research output: Contribution to journalArticle

17 Scopus citations


The mechanisms underlying transcriptional activation and repression have become much clearer. Recent evidence suggests that transcription factors that do not bind DNA directly, the co-activators and co-repressors, mediate a large number of cell signaling events. Their association with histone acetylases, to mediate activation, or deacetylases, to mediate repression, provide a model for explaining how gene expression is regulated.

Original languageEnglish (US)
Pages (from-to)413-417
Number of pages5
JournalCurrent Opinion in Neurobiology
Issue number3
StatePublished - Jun 1998

ASJC Scopus subject areas

  • Neuroscience(all)

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